Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50029891
TargetMetabotropic glutamate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50263669((1aS,7aS)-7-(hydroxyimino)-N-phenyl-1,1a,7,7a-tetr...)
Affinity DataIC50: 3.00E+3nMAssay Description:Compound was tested for inhibition of glutamate-evoked (10 uM) [Ca2+] mobilization in mGluR1-alpha expressed-CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMetabotropic glutamate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289106(2-[(E)-Hydroxyimino]-1a,2-dihydro-1H-7-oxa-cyclopr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for inhibition of glutamate-evoked (10 uM) [Ca2+] mobilization in mGluR1-alpha expressed-CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMetabotropic glutamate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM86213(CAS_5126051 | CHEMBL327783 | NSC_5126051 | CPCCOEt)
Affinity DataIC50: 2.30E+4nMAssay Description:Compound was tested for inhibition of glutamate-evoked (10 uM) [Ca2+] mobilization in mGluR1-alpha expressed-CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMetabotropic glutamate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50030628(CHEMBL444589 | 4-(Amino-carboxy-methyl)-2-hydroxy-...)
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was tested for inhibition of glutamate-evoked (10 uM) [Ca2+] mobilization in mGluR1-alpha expressed-CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMetabotropic glutamate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50030627(CHEMBL299683 | MCPG | (R,S)-alpha-Methyl-4-carboxy...)
Affinity DataIC50: 7.00E+5nMAssay Description:Compound was tested for inhibition of glutamate-evoked (10 uM) [Ca2+] mobilization in mGluR1-alpha expressed-CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article
PDB3D3D Structure (crystal)