Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50021268
TargetPoly [ADP-ribose] polymerase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638922(CHEMBL5558410)
Affinity DataIC50: 2.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM715312(US20250026748, Compound 476)
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM715312(US20250026748, Compound 476)
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638920(CHEMBL5556723)
Affinity DataIC50: 4.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638922(CHEMBL5558410)
Affinity DataIC50: 5.40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 8.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638922(CHEMBL5558410)
Affinity DataIC50: 46nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638922(CHEMBL5558410)
Affinity DataIC50: 51nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638921(CHEMBL5555891)
Affinity DataIC50: 60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638920(CHEMBL5556723)
Affinity DataIC50: 72nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638919(CHEMBL5564238)
Affinity DataIC50: 79nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638922(CHEMBL5558410)
Affinity DataIC50: 88nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638914(CHEMBL5558738)
Affinity DataIC50: 117nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638922(CHEMBL5558410)
Affinity DataIC50: 156nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638912(CHEMBL5556040)
Affinity DataIC50: 166nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638922(CHEMBL5558410)
Affinity DataIC50: 194nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM714977(US20250026748, Compound 141)
Affinity DataIC50: 200nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM715312(US20250026748, Compound 476)
Affinity DataIC50: 200nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638922(CHEMBL5558410)
Affinity DataIC50: 206nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638910(CHEMBL5555002)
Affinity DataIC50: 268nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 292nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 382nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 631nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 660nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638918(CHEMBL5558038)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638917(CHEMBL5564092)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638916(CHEMBL5556293)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638915(CHEMBL5559805)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638913(CHEMBL5567364)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638911(CHEMBL5558560)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638922(CHEMBL5558410)
Affinity DataIC50: 1.10E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 1.79E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638922(CHEMBL5558410)
Affinity DataIC50: 2.93E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50226181(Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...)
Affinity DataIC50: 2.40E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50226181(Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...)
Affinity DataIC50: 2.44E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase theta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50226181(Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...)
Affinity DataIC50: 9.23E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed