Compile Data Set for Download or QSAR
Report error Found 62 Enz. Inhib. hit(s) with all data for entry = 50020548
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM76986(3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-pipe...)
Affinity DataEC50:  20nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631139(CHEMBL5437182)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631140(CHEMBL5403728)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631141(CHEMBL5398719)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631142(CHEMBL5394519)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631143(CHEMBL5430384)
Affinity DataEC50:  70nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631144(CHEMBL5428693)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631145(CHEMBL5407904)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631146(CHEMBL5427975)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631147(CHEMBL5427589)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631148(CHEMBL5410293)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631149(CHEMBL5419778)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631150(CHEMBL5408444)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50070114(CHEMBL468 | 2-(2,6-dioxopiperidin-3-yl)isoindoline...)
Affinity DataEC50:  330nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM65454(Lenalidomide | US9694015, 6.1 | 191732-72-6 | Revl...)
Affinity DataEC50:  70nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM65456(pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...)
Affinity DataEC50:  20nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM581736(US11512080, Compound I-27)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM65497(CC-220 (Compound 6) | US9694015, 6.4S)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50631139(CHEMBL5437182)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50631140(CHEMBL5403728)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50631141(CHEMBL5398719)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50631142(CHEMBL5394519)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50631143(CHEMBL5430384)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50631144(CHEMBL5428693)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50631145(CHEMBL5407904)
Affinity DataEC50:  21nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50631146(CHEMBL5427975)
Affinity DataEC50:  100nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50631147(CHEMBL5427589)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50631148(CHEMBL5410293)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50631149(CHEMBL5419778)
Affinity DataEC50:  70nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50631150(CHEMBL5408444)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50631119(CHEMBL4170596)
Affinity DataEC50:  0.300nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631129(CHEMBL5406902)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631119(CHEMBL4170596)
Affinity DataEC50:  5nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM631083(US11802131, Example 10 | N-(2,6-dioxo-3-piperidyl)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50630590(CHEMBL5398662)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50630592(CHEMBL5424655)
Affinity DataEC50:  607nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM575328(US11459335, Compound 125 | US20230279023, Compound...)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631120(CHEMBL5409457)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631121(CHEMBL5428097)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM575330(US11512080, Compound I-103 | US11459335, Compound ...)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631122(CHEMBL5413234)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631123(CHEMBL5438154)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631124(CHEMBL5417302)
Affinity DataEC50:  130nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631125(CHEMBL5402512)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631126(CHEMBL5427029)
Affinity DataEC50:  312nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631127(CHEMBL5412109)
Affinity DataEC50:  142nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631128(CHEMBL5424221)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM65497(CC-220 (Compound 6) | US9694015, 6.4S)
Affinity DataEC50:  1nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM475126(US10849982, Compd # 37)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50631130(CHEMBL5420425)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged Aiolos degradation in human DF15 cells incubated for 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
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