Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50020245
Target5-hydroxytryptamine receptor 2B(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM84994(NSC_163091 | CAS_163091 | ORG-5222)
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]-LSD from human 5-HT2B receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataKi:  0.360nMAssay Description:Displacement of [3H]-LSD from human 5-HT2B receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50056445(lisuride, (S) | lisuride | N'-((8alpha)-9,10-Dideh...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-5HT from human 5-HT2B receptor expressed in CHO-K1 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50017721(5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclop...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-5HT from human 5-HT2B receptor expressed in CHO-K1 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  7.20nMAssay Description:Displacement of [3H]-5HT from human 5-HT2B receptor expressed in african green monkey COS7 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50222218(CHEBI:51137 | Mianserin)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]-5HT from human 5-HT2B receptor expressed in african green monkey COS7 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM85530(Norfenfluramine (+) | Norfenfluramine | Nor-dexfen...)
Affinity DataKi:  11nMAssay Description:Binding affinity to human 5-HT2B receptor expressed in african green monkey COS7 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-5HT from human 5-HT2B receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM81790(NSC_2159 | CAS_71675-85-9 | Amisulpride | US101672...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-LSD from human 5-HT2B receptor assessed as inhibition constant incubated for 1.5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50003359(CHEMBL73149 | LY 246708 | CHEMBL21536 | 5-(4-Hexyl...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-5HT from human 5-HT2B receptor expressed in human SH-SY5Y cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50628061(CHEMBL5425738)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]-LSD from human 5-HT2B receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50001885(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]-5HT from human 5-HT2B receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50013515(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]-5HT from human 5-HT2B receptor expressed in african green monkey COS7 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50073444(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2...)
Affinity DataKi:  74nMAssay Description:Displacement of [3H]-5HT from human 5-HT2B receptor expressed in african green monkey COS7 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50095890(2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-...)
Affinity DataKi:  86nMAssay Description:Displacement of [3H]-LSD from human 5-HT2B receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed