Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50019741
TargetSphingosine 1-phosphate receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50622637(CHEMBL5403266)
Affinity DataIC50: 3nMAssay Description:Inhibition of human S1P1 expressed in human HeLa cells incubated for 20 mins by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandPNGBDBM50323726(2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tol...)
Affinity DataIC50: 13nMAssay Description:Inhibition of PI3K delta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSphingosine 1-phosphate receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50622636(CHEMBL5431184)
Affinity DataIC50: 170nMAssay Description:Inhibition of human S1P1 expressed in human HeLa cells incubated for 20 mins by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed