Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50015189
TargetGenome polyprotein(DENV-2)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50583557(CHEMBL5075993)
Affinity DataIC50: 6nMAssay Description:Inhibition of DENV NS2B-NS3 protease assessed as fluorescence emission using benzoyl-Nle-Lys-Arg-Arg-AMC as substrate preincubated with enzyme for 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGenome polyprotein(DENV-2)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50583558(CHEMBL5075008)
Affinity DataIC50: 9nMAssay Description:Inhibition of DENV NS2B-NS3 protease assessed as fluorescence emission using benzoyl-Nle-Lys-Arg-Arg-AMC as substrate preincubated with enzyme for 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGenome polyprotein(DENV-2)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50583559(CHEMBL5092085)
Affinity DataIC50: 12nMAssay Description:Inhibition of DENV NS2B-NS3 protease assessed as fluorescence emission using benzoyl-Nle-Lys-Arg-Arg-AMC as substrate preincubated with enzyme for 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGenome polyprotein(DENV-2)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50583560(CHEMBL5081752)
Affinity DataIC50: 74nMAssay Description:Inhibition of DENV NS2B-NS3 protease assessed as fluorescence emission using benzoyl-Nle-Lys-Arg-Arg-AMC as substrate preincubated with enzyme for 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGenome polyprotein(DENV-2)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50583556(CHEMBL5083861)
Affinity DataIC50: 500nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease expressed in Escherichia coli assessed as fluorescence emission using Bz-nKRR-AMC as substrate by microplate re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGenome polyprotein(DENV-2)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50583556(CHEMBL5083861)
Affinity DataIC50: 500nMAssay Description:Inhibition of DENV NS2B-NS3 protease assessed as fluorescence emission using benzoyl-Nle-Lys-Arg-Arg-AMC as substrate preincubated with enzyme for 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGenome polyprotein(DENV-2)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50583557(CHEMBL5075993)
Affinity DataKi:  665nMAssay Description:Binding affinity to DENV NS2B-NS3 protease assessed as inhibition constant using benzoyl-Nle-Lys-Arg-Arg-AMC as substrate incubated for 60 min by mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGenome polyprotein(DENV-2)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50583556(CHEMBL5083861)
Affinity DataKi:  7.25E+3nMAssay Description:Binding affinity to DENV NS2B-NS3 protease assessed as inhibition constant using benzoyl-Nle-Lys-Arg-Arg-AMC as substrate incubated for 60 min by mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed