Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50015881
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Human)
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50590283(CHEMBL5169766 | US20230303547, Reference Example D...)
Affinity DataIC50: 10nMAssay Description:Inhibition of GST-tagged recombinant UCHL3 (unknown origin) using Ub-Lys-TAMRA as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Human)
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50590284(CHEMBL5192316)
Affinity DataIC50: 10nMAssay Description:Inhibition of GST-tagged recombinant UCHL3 (unknown origin) using Ub-Lys-TAMRA as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50590283(CHEMBL5169766 | US20230303547, Reference Example D...)
Affinity DataIC50: 550nMAssay Description:Inhibition of FLAG-tagged UCHL1 (unknown origin) expressed in CAL-51 cells using HA-Ub-VME as substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50590283(CHEMBL5169766 | US20230303547, Reference Example D...)
Affinity DataIC50: 580nMAssay Description:Inhibition of GST-tagged recombinant UCHL1 (unknown origin) using Ub-Lys-TAMRA as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50590284(CHEMBL5192316)
Affinity DataIC50: 600nMAssay Description:Inhibition of GST-tagged recombinant UCHL1 (unknown origin) using Ub-Lys-TAMRA as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50590284(CHEMBL5192316)
Affinity DataIC50: 830nMAssay Description:Inhibition of FLAG-tagged UCHL1 (unknown origin) expressed in CAL-51 cells using HA-Ub-VME as substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed