Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50014123
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50572906(CHEMBL4854665)
Affinity DataIC50: 10nMAssay Description:Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50572907(CHEMBL4850503)
Affinity DataIC50: 10nMAssay Description:Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50572908(CHEMBL4872977)
Affinity DataIC50: 10nMAssay Description:Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50572909(CHEMBL4856985)
Affinity DataIC50: 10nMAssay Description:Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50572910(CHEMBL4861007)
Affinity DataIC50: 10nMAssay Description:Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50572911(CHEMBL4852677)
Affinity DataIC50: 10nMAssay Description:Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50572906(CHEMBL4854665)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50572907(CHEMBL4850503)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50572908(CHEMBL4872977)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50572909(CHEMBL4856985)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50572910(CHEMBL4861007)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50572911(CHEMBL4852677)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed