Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50018362
TargetEpidermal growth factor receptor(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50587891(CHEMBL5181237 | US11814388, Compound 4)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of EGFR (unknown origin) using Poly(Glu, Tyr) as substrate incubated for 45 mins in presence of ATP by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50486734(CHEMBL5289303)
Affinity DataIC50: 12nMAssay Description:Inhibition of VEGFR2 (unknown origin) at 25 nM using Poly(Glu, Tyr) as substrate by Kinase-Glo plus luminescent kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50486735(CHEMBL5274698)
Affinity DataIC50: 14nMAssay Description:Inhibition of VEGFR2 (unknown origin) at 25 nM using Poly(Glu, Tyr) as substrate by Kinase-Glo plus luminescent kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAurora kinase A(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50587891(CHEMBL5181237 | US11814388, Compound 4)
Affinity DataIC50: 1.99E+3nMAssay Description:Inhibition of AURKA (unknown origin) in presence of ATP by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed