Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50009436
TargetEpidermal growth factor receptor(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (695 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528844(CHEMBL4516916)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HER4 (682 to 993 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528843(CHEMBL4516736)
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HER2 (676 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 2.59E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HER4 (682 to 993 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528844(CHEMBL4516916)
Affinity DataIC50: 3.28E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged IGF1R (960 to end residues) expressed in baculovirus infected Sf9 insect cells using IGF1Rtide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528843(CHEMBL4516736)
Affinity DataIC50: 4.34E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (695 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528843(CHEMBL4516736)
Affinity DataIC50: 4.68E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HER4 (682 to 993 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528842(CHEMBL4557318)
Affinity DataIC50: 4.71E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (695 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 5.06E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDR (789 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528844(CHEMBL4516916)
Affinity DataIC50: 6.96E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HER2 (676 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 8.12E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDGFRalpha (550 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528844(CHEMBL4516916)
Affinity DataIC50: 9.79E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged INSR (1011 to end residues) expressed in baculovirus infected Sf9 insect cells using Axltide as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528843(CHEMBL4516736)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged IGF1R (960 to end residues) expressed in baculovirus infected Sf9 insect cells using IGF1Rtide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528844(CHEMBL4516916)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDR (789 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528843(CHEMBL4516736)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDR (789 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528844(CHEMBL4516916)
Affinity DataIC50: 2.33E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (695 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528842(CHEMBL4557318)
Affinity DataIC50: 2.56E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDR (789 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528842(CHEMBL4557318)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HER4 (682 to 993 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528842(CHEMBL4557318)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDGFRalpha (550 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528844(CHEMBL4516916)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDGFRalpha (550 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDGFRbeta (557 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528843(CHEMBL4516736)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDGFRbeta (557 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528842(CHEMBL4557318)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDGFRbeta (557 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged IGF1R (960 to end residues) expressed in baculovirus infected Sf9 insect cells using IGF1Rtide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528844(CHEMBL4516916)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDGFRbeta (557 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528842(CHEMBL4557318)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HER2 (676 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528843(CHEMBL4516736)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDGFRalpha (550 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged INSR (1011 to end residues) expressed in baculovirus infected Sf9 insect cells using Axltide as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528842(CHEMBL4557318)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged INSR (1011 to end residues) expressed in baculovirus infected Sf9 insect cells using Axltide as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528842(CHEMBL4557318)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged IGF1R (960 to end residues) expressed in baculovirus infected Sf9 insect cells using IGF1Rtide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HER2 (676 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528843(CHEMBL4516736)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged INSR (1011 to end residues) expressed in baculovirus infected Sf9 insect cells using Axltide as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed