Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50002524
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM347642(2-((4-(1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl)p...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant PDE10A (unknown origin) using cAMP/cGMP as substrate incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM347639(4-(1-methyl-3-(4-((1-methyl-1H-imidazol-2-yl)ethyn...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant PDE10A (unknown origin) using cAMP/cGMP as substrate incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM347635(2-((4-(1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl)p...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant PDE10A (unknown origin) using cAMP/cGMP as substrate incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM347659(2-[2-[2-methoxy-4-[1-methyl-4-(4-pyridyl)pyrazol-3...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant PDE10A (unknown origin) using cAMP/cGMP as substrate incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM347647(2-[2-[4-[1-methyl-4-(4-pyridyl)pyrazol-3-yl]phenyl...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant PDE10A (unknown origin) using cAMP/cGMP as substrate incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM347652(2-methyl-6-[2-[4-[1-methyl-4-(1H-pyrazol-4-yl)pyra...)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant PDE10A (unknown origin) using cAMP/cGMP as substrate incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed