Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50002677
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461533(Emricasan | IDN-6556 | PF-03491390 | VAY-785 | VAY...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461525(CHEMBL4228386)
Affinity DataIC50: 6nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461503(CHEMBL4225291)
Affinity DataIC50: 6nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461502(CHEMBL4224765)
Affinity DataIC50: 6nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461528(CHEMBL4228658)
Affinity DataIC50: 7nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461506(CHEMBL4227628)
Affinity DataIC50: 9nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461520(CHEMBL4226868)
Affinity DataIC50: 10nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461505(CHEMBL4228438)
Affinity DataIC50: 10nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461494(CHEMBL4228922)
Affinity DataIC50: 11nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461517(CHEMBL4224702)
Affinity DataIC50: 12nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461501(CHEMBL4226499)
Affinity DataIC50: 12nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461521(CHEMBL4227309)
Affinity DataIC50: 14nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461519(CHEMBL4228290)
Affinity DataIC50: 14nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461523(CHEMBL4228349)
Affinity DataIC50: 14nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461497(CHEMBL4226345)
Affinity DataIC50: 14nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461499(CHEMBL4228280)
Affinity DataIC50: 16nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461518(CHEMBL4227988)
Affinity DataIC50: 18nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461493(CHEMBL4227888)
Affinity DataIC50: 18nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461488(CHEMBL4228603)
Affinity DataIC50: 19nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461504(CHEMBL4226512)
Affinity DataIC50: 20nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461498(CHEMBL4227101)
Affinity DataIC50: 20nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461530(CHEMBL4227032)
Affinity DataIC50: 20nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461500(CHEMBL4224986)
Affinity DataIC50: 20nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461513(CHEMBL4228595)
Affinity DataIC50: 21nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461496(CHEMBL4227507)
Affinity DataIC50: 22nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461495(CHEMBL4227831)
Affinity DataIC50: 23nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461524(CHEMBL4225592)
Affinity DataIC50: 24nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461507(CHEMBL4226305)
Affinity DataIC50: 25nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461492(CHEMBL4228543)
Affinity DataIC50: 26nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461529(CHEMBL4225476)
Affinity DataIC50: 27nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461508(CHEMBL4226326)
Affinity DataIC50: 27nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461526(CHEMBL4227607)
Affinity DataIC50: 30nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461516(CHEMBL4226811)
Affinity DataIC50: 30nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461489(CHEMBL4225235)
Affinity DataIC50: 35nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461509(CHEMBL4228374)
Affinity DataIC50: 40nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461522(CHEMBL4226046)
Affinity DataIC50: 44nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461512(CHEMBL4228733)
Affinity DataIC50: 64nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461511(CHEMBL4226573)
Affinity DataIC50: 75nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461527(CHEMBL4227939)
Affinity DataIC50: 79nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461510(CHEMBL4226004)
Affinity DataIC50: 108nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461490(CHEMBL4227107)
Affinity DataIC50: 112nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461515(CHEMBL4225855)
Affinity DataIC50: 138nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461491(CHEMBL4228141)
Affinity DataIC50: 142nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461532(CHEMBL4226560)
Affinity DataIC50: 142nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461514(CHEMBL4227026)
Affinity DataIC50: 213nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461531(CHEMBL4224869)
Affinity DataIC50: 244nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed