Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50000145
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241583(CHEMBL4067152)
Affinity DataEC50:  980nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241569(CHEMBL4062426)
Affinity DataEC50:  165nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241573(CHEMBL4098112)
Affinity DataEC50:  1.71E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241574(CHEMBL4071064)
Affinity DataEC50:  2.34E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241575(CHEMBL4067875)
Affinity DataEC50:  46nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241575(CHEMBL4067875)
Affinity DataEC50:  70nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing chimeric G protein assessed as increase in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241575(CHEMBL4067875)
Affinity DataEC50:  27nMAssay Description:Positive allosteric modulation of rat mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241576(CHEMBL4061970)
Affinity DataEC50:  53nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241577(CHEMBL4070594)
Affinity DataEC50:  4nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241578(CHEMBL4105462)
Affinity DataEC50:  6nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241579(CHEMBL4081211)
Affinity DataEC50:  53nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241580(CHEMBL4089083)
Affinity DataEC50:  79nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241580(CHEMBL4089083)
Affinity DataEC50:  47nMAssay Description:Positive allosteric modulation of rat mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241581(CHEMBL4079161)
Affinity DataEC50:  200nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241568(CHEMBL4100586)
Affinity DataEC50:  35nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241584(CHEMBL4072639)
Affinity DataEC50:  5.26E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241585(CHEMBL4077754)
Affinity DataEC50:  1.16E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241580(CHEMBL4089083)
Affinity DataEC50: >1.50E+4nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing chimeric G protein assessed as increase in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241586(CHEMBL4095448)
Affinity DataEC50:  1.42E+4nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241587(CHEMBL4082331)
Affinity DataEC50:  6.99E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241588(CHEMBL4098106)
Affinity DataEC50:  110nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241589(CHEMBL4097743)
Affinity DataEC50:  4nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241590(CHEMBL4067872)
Affinity DataEC50:  60nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241591(CHEMBL4078081)
Affinity DataEC50:  1.63E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241592(CHEMBL4090015)
Affinity DataEC50:  17nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241593(CHEMBL4092850)
Affinity DataEC50:  19nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241594(CHEMBL4082573)
Affinity DataEC50:  10nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241595(CHEMBL4098128)
Affinity DataEC50:  150nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241554(CHEMBL4063474)
Affinity DataEC50:  35nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50116514(CHEMBL507522)
Affinity DataEC50:  2.50E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing chimeric G protein assessed as increase in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241541(CHEMBL4087749)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241542(CHEMBL4065348)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241543(CHEMBL4060429)
Affinity DataEC50:  3.96E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241544(CHEMBL4081595)
Affinity DataEC50:  310nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241545(CHEMBL4059644)
Affinity DataEC50:  1.27E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241546(CHEMBL4071024)
Affinity DataEC50:  240nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241547(CHEMBL4097178)
Affinity DataEC50:  130nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241548(CHEMBL4089473)
Affinity DataEC50:  280nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241549(CHEMBL4068295)
Affinity DataEC50:  860nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241550(CHEMBL4067271)
Affinity DataEC50:  50nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241551(CHEMBL4088412)
Affinity DataEC50:  2.47E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241552(CHEMBL4085101)
Affinity DataEC50:  90nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50116514(CHEMBL507522)
Affinity DataEC50:  2.25E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241555(CHEMBL4062968)
Affinity DataEC50:  160nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241556(CHEMBL4083118)
Affinity DataEC50:  1.74E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241557(CHEMBL4101095)
Affinity DataEC50:  3.01E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241559(CHEMBL4093353)
Affinity DataEC50:  9.84E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241560(CHEMBL4064041)
Affinity DataEC50:  750nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241561(CHEMBL4085608)
Affinity DataEC50:  1.01E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241562(CHEMBL4103895)
Affinity DataEC50:  1.72E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
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