Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50040095
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389109(CHEMBL2064557)
Affinity DataEC50:  810nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389123(CHEMBL2064631)
Affinity DataEC50:  1nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389122(CHEMBL2064629)
Affinity DataEC50:  16nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389121(CHEMBL2064628)
Affinity DataEC50:  4nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389120(CHEMBL2064565)
Affinity DataEC50:  28nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389119(CHEMBL2064564)
Affinity DataEC50:  15nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389118(CHEMBL2064563)
Affinity DataEC50:  36nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389117(CHEMBL2064562)
Affinity DataEC50:  9nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389116(CHEMBL2064561)
Affinity DataEC50:  11nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389115(CHEMBL2064560)
Affinity DataEC50:  21nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389108(CHEMBL2064632)
Affinity DataEC50:  7nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389110(CHEMBL2064630)
Affinity DataEC50:  18nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389113(CHEMBL2064558)
Affinity DataEC50:  32nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389111(CHEMBL2064555)
Affinity DataEC50:  12.6nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase MARK1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389121(CHEMBL2064628)
Affinity DataIC50: 115nMAssay Description:Inhibition of MARK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389121(CHEMBL2064628)
Affinity DataIC50: 170nMAssay Description:Inhibition of Erk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389121(CHEMBL2064628)
Affinity DataIC50: 227nMAssay Description:Inhibition of GSK3betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389121(CHEMBL2064628)
Affinity DataIC50: 450nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389112(CHEMBL2064556)
Affinity DataKi:  2.80nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389111(CHEMBL2064555)
Affinity DataKi:  3.40nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389111(CHEMBL2064555)
Affinity DataKi:  6nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389116(CHEMBL2064561)
Affinity DataKi:  12nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389117(CHEMBL2064562)
Affinity DataKi:  13nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389113(CHEMBL2064558)
Affinity DataKi:  30nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389120(CHEMBL2064565)
Affinity DataKi:  31nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389109(CHEMBL2064557)
Affinity DataKi:  64nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389119(CHEMBL2064564)
Affinity DataKi:  68nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389118(CHEMBL2064563)
Affinity DataKi:  98nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389115(CHEMBL2064560)
Affinity DataKi:  207nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389114(CHEMBL2064559)
Affinity DataKi:  512nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389117(CHEMBL2064562)
Affinity DataKi:  1.16E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389113(CHEMBL2064558)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389116(CHEMBL2064561)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed