Compile Data Set for Download or QSAR
Report error Found 71 Enz. Inhib. hit(s) with all data for entry = 50034641
LigandPNGBDBM50365506(CHEMBL1957497)
Affinity DataEC50:  93nMAssay Description:Inhibition of PI3K p110alpha/p85alpha-mediated AKT1 phosphorylation at Ser473 in human U2OS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365507(CHEMBL1957498)
Affinity DataEC50:  208nMAssay Description:Inhibition of PI3K p110alpha/p85alpha-mediated AKT1 phosphorylation at Ser473 in human U2OS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365508(CHEMBL1957499)
Affinity DataEC50:  203nMAssay Description:Inhibition of PI3K p110alpha/p85alpha-mediated AKT1 phosphorylation at Ser473 in human U2OS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365509(CHEMBL1957500)
Affinity DataEC50:  495nMAssay Description:Inhibition of PI3K p110alpha/p85alpha-mediated AKT1 phosphorylation at Ser473 in human U2OS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365510(CHEMBL1957501)
Affinity DataEC50:  138nMAssay Description:Inhibition of PI3K p110alpha/p85alpha-mediated AKT1 phosphorylation at Ser473 in human U2OS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365511(CHEMBL1957502)
Affinity DataEC50:  600nMAssay Description:Inhibition of PI3K p110alpha/p85alpha-mediated AKT1 phosphorylation at Ser473 in human U2OS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365512(CHEMBL1957503)
Affinity DataEC50:  713nMAssay Description:Inhibition of PI3K p110alpha/p85alpha-mediated AKT1 phosphorylation at Ser473 in human U2OS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365513(CHEMBL1957504)
Affinity DataEC50:  452nMAssay Description:Inhibition of PI3K p110alpha/p85alpha-mediated AKT1 phosphorylation at Ser473 in human U2OS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365514(CHEMBL1957505)
Affinity DataEC50:  429nMAssay Description:Inhibition of PI3K p110alpha/p85alpha-mediated AKT1 phosphorylation at Ser473 in human U2OS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365515(CHEMBL1957506)
Affinity DataEC50:  976nMAssay Description:Inhibition of PI3K p110alpha/p85alpha-mediated AKT1 phosphorylation at Ser473 in human U2OS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365516(CHEMBL1957507)
Affinity DataEC50:  200nMAssay Description:Inhibition of PI3K p110alpha/p85alpha-mediated AKT1 phosphorylation at Ser473 in human U2OS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365517(CHEMBL1957508)
Affinity DataEC50:  114nMAssay Description:Inhibition of PI3K p110alpha/p85alpha-mediated AKT1 phosphorylation at Ser473 in human U2OS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365517(CHEMBL1957508)
Affinity DataIC50: 31nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365515(CHEMBL1957506)
Affinity DataIC50: 35nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365514(CHEMBL1957505)
Affinity DataIC50: 35nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365526(CHEMBL1957492)
Affinity DataIC50: 37nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365513(CHEMBL1957504)
Affinity DataIC50: 38nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365507(CHEMBL1957498)
Affinity DataIC50: 47nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365516(CHEMBL1957507)
Affinity DataIC50: 50nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365512(CHEMBL1957503)
Affinity DataIC50: 92nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365506(CHEMBL1957497)
Affinity DataIC50: 95nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365519(CHEMBL1957485)
Affinity DataIC50: 96nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365510(CHEMBL1957501)
Affinity DataIC50: 107nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365521(CHEMBL1957487)
Affinity DataIC50: 108nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365511(CHEMBL1957502)
Affinity DataIC50: 110nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365509(CHEMBL1957500)
Affinity DataIC50: 145nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365508(CHEMBL1957499)
Affinity DataIC50: 194nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365518(CHEMBL1957484)
Affinity DataIC50: 197nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365520(CHEMBL1957486)
Affinity DataIC50: 340nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365523(CHEMBL1957489)
Affinity DataIC50: 444nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365525(CHEMBL1957491)
Affinity DataIC50: 451nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365528(CHEMBL1957494)
Affinity DataIC50: 512nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365530(CHEMBL1957496)
Affinity DataIC50: 526nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365527(CHEMBL1957493)
Affinity DataIC50: 540nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365522(CHEMBL1957488)
Affinity DataIC50: 639nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365529(CHEMBL1957495)
Affinity DataIC50: 897nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365524(CHEMBL1957490)
Affinity DataIC50: 2.75E+3nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365507(CHEMBL1957498)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365517(CHEMBL1957508)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365514(CHEMBL1957505)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365513(CHEMBL1957504)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365511(CHEMBL1957502)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365509(CHEMBL1957500)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365508(CHEMBL1957499)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365506(CHEMBL1957497)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)
Affinity DataIC50: 6.40E+4nMAssay Description:Displacement of [3H]-astemizole from human ERG expressed in CHO-K1 cells membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365506(CHEMBL1957497)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]-astemizole from human ERG expressed in CHO-K1 cells membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365517(CHEMBL1957508)
Affinity DataKi:  2.80nMAssay Description:Inhibition of human PI3K p110delta/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365514(CHEMBL1957505)
Affinity DataKi:  3.60nMAssay Description:Inhibition of human PI3K p110delta/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365513(CHEMBL1957504)
Affinity DataKi:  6.5nMAssay Description:Inhibition of human PI3K p110delta/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
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