Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50032987
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337479(N-(5-chloro-2-(1H-tetrazol-1-yl)benzyl)-3-(4-isopr...)
Affinity DataKi:  0.270nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337483(N1-(5-chloro-2-(1H-tetrazol-1-yl)benzyl)-N3,N3-dii...)
Affinity DataKi:  0.270nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337485(N1-(2-(aminomethyl)-5-chlorobenzyl)-N3,N3-diisobut...)
Affinity DataKi:  0.680nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337487(methyl 2-(4-chloro-2-(2-(3-(diisobutylcarbamoyl)-5...)
Affinity DataKi:  0.730nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337478(3-(3-(5-chloro-2-(1H-tetrazol-1-yl)benzylcarbamoyl...)
Affinity DataKi:  0.770nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337474(N-(5-chloro-2-(1H-tetrazol-1-yl)benzyl)-3-(N-cyclo...)
Affinity DataKi:  0.930nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337488(3-(5-chloro-2-(1H-1,2,4-triazol-1-yl)phenethoxy)-N...)
Affinity DataKi:  0.930nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337472(N-(5-chloro-2-(1H-tetrazol-1-yl)benzyl)-3-(N-cyclo...)
Affinity DataKi:  1.25nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337473(3-((2-aminoethyl)(cyclohexyl)amino)-N-(5-chloro-2-...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337486(3-(5-chloro-2-(2-oxo-2-(piperidin-3-ylamino)ethoxy...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337489(3-(2-(1H-tetrazol-1-yl)phenethoxy)-N,N-diisobutyl-...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337477(N-(5-chloro-2-(1H-tetrazol-1-yl)benzyl)-3-(4-isobu...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337491(3-(2-(aminomethyl)phenethoxy)-N,N-diisobutyl-5-met...)
Affinity DataKi:  2.90nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337493(N,N-diisobutyl-3-methyl-5-(2-(5-methyl-1H-imidazol...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337475(N-(5-chloro-2-(1H-tetrazol-1-yl)benzyl)-3-(N-cyclo...)
Affinity DataKi:  4.10nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337484(N1-(5-chloro-2-(1H-1,2,4-triazol-1-yl)benzyl)-N3,N...)
Affinity DataKi:  7nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337476(N-(5-chloro-2-(1H-tetrazol-1-yl)benzyl)-3-(cyclohe...)
Affinity DataKi:  9.60nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337490(3-(5-chloro-2-methoxyphenethoxy)-N,N-diisobutyl-5-...)
Affinity DataKi:  34nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337492(3-(2,2-difluoro-2-(4-methylpyridin-2-yl)ethoxy)-N,...)
Affinity DataKi:  37nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337482(N1-(2-(1H-tetrazol-1-yl)benzyl)-N3,N3-diisobutyl-5...)
Affinity DataKi:  50nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337481(N-(5-chloro-2-(1H-tetrazol-1-yl)benzyl)-3-(4-(dime...)
Affinity DataKi:  67nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337480(3-(4-acetylpyridin-3-yl)-N-(5-chloro-2-(1H-tetrazo...)
Affinity DataKi:  85nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed