Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50032879
TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50319926(2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...)
Affinity DataIC50: 5nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336025(N-(2-(cyclopropylmethoxy)-4-(2-morpholino-4-oxo-4H...)
Affinity DataIC50: 8nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336024(2-morpholino-N-(5-(2-morpholino-4-oxo-4H-chromen-8...)
Affinity DataIC50: 14nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50156495(NU-7441 | NU-7432 | 8-Dibenzothiophen-4-yl-2-morph...)
Affinity DataIC50: 28nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50336025(N-(2-(cyclopropylmethoxy)-4-(2-morpholino-4-oxo-4H...)
Affinity DataIC50: 70nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336028(N-(2-hydroxy-4-(2-morpholino-4-oxo-4H-chromen-8-yl...)
Affinity DataIC50: 80nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336038(N-(2-((1-methylcyclobutyl)methoxy)-4-(2-morpholino...)
Affinity DataIC50: 110nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50156495(NU-7441 | NU-7432 | 8-Dibenzothiophen-4-yl-2-morph...)
Affinity DataIC50: 130nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50336031(N-(2-isobutoxy-4-(2-morpholino-4-oxo-4H-chromen-8-...)
Affinity DataIC50: 150nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50336032(N-(2-(allyloxy)-4-(2-morpholino-4-oxo-4H-chromen-8...)
Affinity DataIC50: 150nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336036(N-(2-(cyclobutylmethoxy)-4-(2-morpholino-4-oxo-4H-...)
Affinity DataIC50: 160nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336032(N-(2-(allyloxy)-4-(2-morpholino-4-oxo-4H-chromen-8...)
Affinity DataIC50: 170nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336031(N-(2-isobutoxy-4-(2-morpholino-4-oxo-4H-chromen-8-...)
Affinity DataIC50: 180nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50336038(N-(2-((1-methylcyclobutyl)methoxy)-4-(2-morpholino...)
Affinity DataIC50: 270nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336029(N-(2-ethoxy-4-(2-morpholino-4-oxo-4H-chromen-8-yl)...)
Affinity DataIC50: 280nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50336036(N-(2-(cyclobutylmethoxy)-4-(2-morpholino-4-oxo-4H-...)
Affinity DataIC50: 290nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50336030(N-(2-isopropoxy-4-(2-morpholino-4-oxo-4H-chromen-8...)
Affinity DataIC50: 290nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336027(N-(2-methoxy-4-(2-morpholino-4-oxo-4H-chromen-8-yl...)
Affinity DataIC50: 290nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50336026(N-(2-((3-methyloxetan-3-yl)methoxy)-4-(2-morpholin...)
Affinity DataIC50: 300nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336030(N-(2-isopropoxy-4-(2-morpholino-4-oxo-4H-chromen-8...)
Affinity DataIC50: 330nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50336027(N-(2-methoxy-4-(2-morpholino-4-oxo-4H-chromen-8-yl...)
Affinity DataIC50: 350nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50336037(N-(2-(2-cyclopropylethoxy)-4-(2-morpholino-4-oxo-4...)
Affinity DataIC50: 400nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50336028(N-(2-hydroxy-4-(2-morpholino-4-oxo-4H-chromen-8-yl...)
Affinity DataIC50: 430nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50336029(N-(2-ethoxy-4-(2-morpholino-4-oxo-4H-chromen-8-yl)...)
Affinity DataIC50: 470nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336037(N-(2-(2-cyclopropylethoxy)-4-(2-morpholino-4-oxo-4...)
Affinity DataIC50: 500nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM12915(CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...)
Affinity DataIC50: 500nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336026(N-(2-((3-methyloxetan-3-yl)methoxy)-4-(2-morpholin...)
Affinity DataIC50: 690nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336039(N-(2-(2-hydroxyethoxy)-4-(2-morpholino-4-oxo-4H-ch...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50336033(N-(2-(2-amino-2-oxoethoxy)-4-(2-morpholino-4-oxo-4...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM12915(CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50336034(N-(2-(2-methoxyethoxy)-4-(2-morpholino-4-oxo-4H-ch...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50336039(N-(2-(2-hydroxyethoxy)-4-(2-morpholino-4-oxo-4H-ch...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336034(N-(2-(2-methoxyethoxy)-4-(2-morpholino-4-oxo-4H-ch...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50336040(N-(2-(2-aminoethoxy)-4-(2-morpholino-4-oxo-4H-chro...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336033(N-(2-(2-amino-2-oxoethoxy)-4-(2-morpholino-4-oxo-4...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50336035(2-morpholino-N-(4-(2-morpholino-4-oxo-4H-chromen-8...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336035(2-morpholino-N-(4-(2-morpholino-4-oxo-4H-chromen-8...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336040(N-(2-(2-aminoethoxy)-4-(2-morpholino-4-oxo-4H-chro...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed