Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50038914
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50378119(CHEMBL1204125)
Affinity DataEC50:  5.50E+3nMAssay Description:Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298003((+/-)-5-(2-fluoropyridin-3-yl)-3-(1H-tetrazol-5-yl...)
Affinity DataEC50:  3.80E+3nMAssay Description:Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297995((+/-)-5-(2-fluorophenyl)-4,5,6,7-tetrahydro-1H-ind...)
Affinity DataEC50:  4.40E+3nMAssay Description:Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297996((+/-)-5-phenyl-4,5,6,7-tetrahydro-1H-indazole-3-ca...)
Affinity DataEC50:  2.80E+4nMAssay Description:Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298002((+/-)-5-(2,5-difluorophenyl)-3-(1H-tetrazol-5-yl)-...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297997((+/-)-5-(2-chlorophenyl)-4,5,6,7-tetrahydro-1H-ind...)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298001(5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-ind...)
Affinity DataEC50:  2.30E+3nMAssay Description:Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298001(5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-ind...)
Affinity DataEC50:  4.50E+3nMAssay Description:Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297999(CHEMBL542000 | 5-(2,5-difluorophenyl)-4,5,6,7-tetr...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298000((+/-)-5-(2,3,5-trifluorophenyl)-4,5,6,7-tetrahydro...)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297999(CHEMBL542000 | 5-(2,5-difluorophenyl)-4,5,6,7-tetr...)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298000((+/-)-5-(2,3,5-trifluorophenyl)-4,5,6,7-tetrahydro...)
Affinity DataIC50: 67nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297999(CHEMBL542000 | 5-(2,5-difluorophenyl)-4,5,6,7-tetr...)
Affinity DataIC50: 90nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in presence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298002((+/-)-5-(2,5-difluorophenyl)-3-(1H-tetrazol-5-yl)-...)
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50378119(CHEMBL1204125)
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50378119(CHEMBL1204125)
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in presence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298001(5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-ind...)
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297999(CHEMBL542000 | 5-(2,5-difluorophenyl)-4,5,6,7-tetr...)
Affinity DataIC50: 220nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297995((+/-)-5-(2-fluorophenyl)-4,5,6,7-tetrahydro-1H-ind...)
Affinity DataIC50: 270nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298001(5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-ind...)
Affinity DataIC50: 370nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in presence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297999(CHEMBL542000 | 5-(2,5-difluorophenyl)-4,5,6,7-tetr...)
Affinity DataIC50: 400nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in presence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297997((+/-)-5-(2-chlorophenyl)-4,5,6,7-tetrahydro-1H-ind...)
Affinity DataIC50: 460nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298003((+/-)-5-(2-fluoropyridin-3-yl)-3-(1H-tetrazol-5-yl...)
Affinity DataIC50: 500nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298001(5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-ind...)
Affinity DataIC50: 600nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298001(5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-ind...)
Affinity DataIC50: 850nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in presence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297998((+/-)-5-(2,6-difluorophenyl)-4,5,6,7-tetrahydro-1H...)
Affinity DataIC50: 2.50E+4nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in presence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed