Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50038308
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50374647(CHEMBL256608)
Affinity DataEC50:  6.50E+4nMAssay Description:Agonist activity at human recombinant GABAc rho1 receptor expressed in Xenopus laevis oocytes at -60mV by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50021187(R(-)-4-amino-3-hydroxybutanoic acid | CHEMBL290216...)
Affinity DataEC50:  1.91E+4nMAssay Description:Agonist activity at human recombinant GABAc rho1 receptor expressed in Xenopus laevis oocytes at -60mV by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataEC50:  1.19E+3nMAssay Description:Agonist activity at human recombinant GABAc rho1 receptor expressed in Xenopus laevis oocytes at -60mV by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50021186(CHEMBL296263 | S(+)-4-amino-3-hydroxybutanoic acid...)
Affinity DataEC50:  4.48E+4nMAssay Description:Agonist activity at human recombinant GABAc rho1 receptor expressed in Xenopus laevis oocytes at -60mV by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50374648(CHEMBL403157)
Affinity DataEC50:  4.00E+4nMAssay Description:Agonist activity at human recombinant GABAc rho1 receptor expressed in Xenopus laevis oocytes at -60mV by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM24189(CHEMBL113304 | [(2S)-3-amino-2-hydroxypropyl](meth...)
Affinity DataIC50: 5.40E+3nMAssay Description:Antagonist activity at human recombinant GABAc rho1 receptor expressed in Xenopus laevis oocytes at -60mV by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50374650(CHEMBL257443)
Affinity DataIC50: 1.60E+4nMAssay Description:Antagonist activity at human recombinant GABAc rho1 receptor expressed in Xenopus laevis oocytes at -60mV by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM24189(CHEMBL113304 | [(2S)-3-amino-2-hydroxypropyl](meth...)
Affinity DataIC50: 1.71E+4nMAssay Description:Antagonist activity at human recombinant GABAc rho1 receptor expressed in Xenopus laevis oocytes at -60mV by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50374649(CHEMBL257442)
Affinity DataIC50: 8.90E+5nMAssay Description:Antagonist activity at human recombinant GABAc rho1 receptor expressed in Xenopus laevis oocytes at -60mV by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed