Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50018287
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193985(3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino...)
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193979(3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino...)
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193972(3-(2-bromophenyl)-2-cyano-1-(2-hydroxy-4-methyl-3-...)
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193971(3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino...)
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193980(3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino...)
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193974(6-chloro-3-({(cyanoimino)[(2-fluorophenyl)amino]me...)
Affinity DataIC50: 9nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193978(3-(2-bromophenyl)-1-[4-chloro-3-({3-[(2R,6S)-2,6-d...)
Affinity DataIC50: 9nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193970(3-[2-(benzyloxy)phenyl]-1-[4-chloro-3-(dimethylsul...)
Affinity DataIC50: 9nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193981(6-chloro-3-[((cyanoimino){[2-(trifluoromethyl)phen...)
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193982(3-(2-bromophenyl)-2-cyano-1-(2-hydroxy-3-{[3-(morp...)
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193977(1-[4-chloro-3-(dimethylsulfamoyl)-2-hydroxyphenyl]...)
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193984(6-chloro-3-({(cyanoimino)[(2-ethylphenyl)amino]met...)
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193973((R)-1-(3-(3-(3-(2-bromophenyl)-2-cyanoguanidino)-6...)
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193976(1-[4-chloro-3-({3-[(2R,6S)-2,6-dimethylmorpholin-4...)
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193986(6-chloro-3-({(cyanoimino)[(2-methylphenyl)amino]me...)
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193973((R)-1-(3-(3-(3-(2-bromophenyl)-2-cyanoguanidino)-6...)
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]IL8 from CXCR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193969(1-(3-{[3-(4-aminopiperidin-1-yl)pentan-3-yl]sulfam...)
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193975(6-chloro-3-{[[(3-chloro-2-fluorophenyl)amino](cyan...)
Affinity DataIC50: 29nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193979(3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino...)
Affinity DataIC50: 55nMAssay Description:Displacement of [125I]IL8 from CXCR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193971(3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino...)
Affinity DataIC50: 100nMAssay Description:Displacement of [125I]IL8 from CXCR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193972(3-(2-bromophenyl)-2-cyano-1-(2-hydroxy-4-methyl-3-...)
Affinity DataIC50: 104nMAssay Description:Displacement of [125I]IL8 from CXCR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193983(1-[4-chloro-3-(dimethylsulfamoyl)-2-hydroxyphenyl]...)
Affinity DataIC50: 112nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193980(3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino...)
Affinity DataIC50: 187nMAssay Description:Displacement of [125I]IL8 from CXCR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193969(1-(3-{[3-(4-aminopiperidin-1-yl)pentan-3-yl]sulfam...)
Affinity DataIC50: 188nMAssay Description:Displacement of [125I]IL8 from CXCR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193985(3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino...)
Affinity DataIC50: 192nMAssay Description:Displacement of [125I]IL8 from CXCR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193978(3-(2-bromophenyl)-1-[4-chloro-3-({3-[(2R,6S)-2,6-d...)
Affinity DataIC50: 215nMAssay Description:Displacement of [125I]IL8 from CXCR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193970(3-[2-(benzyloxy)phenyl]-1-[4-chloro-3-(dimethylsul...)
Affinity DataIC50: 293nMAssay Description:Displacement of [125I]IL8 from CXCR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193986(6-chloro-3-({(cyanoimino)[(2-methylphenyl)amino]me...)
Affinity DataIC50: 378nMAssay Description:Displacement of [125I]IL8 from CXCR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193981(6-chloro-3-[((cyanoimino){[2-(trifluoromethyl)phen...)
Affinity DataIC50: 411nMAssay Description:Displacement of [125I]IL8 from CXCR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193984(6-chloro-3-({(cyanoimino)[(2-ethylphenyl)amino]met...)
Affinity DataIC50: 512nMAssay Description:Displacement of [125I]IL8 from CXCR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193982(3-(2-bromophenyl)-2-cyano-1-(2-hydroxy-3-{[3-(morp...)
Affinity DataIC50: 582nMAssay Description:Displacement of [125I]IL8 from CXCR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193977(1-[4-chloro-3-(dimethylsulfamoyl)-2-hydroxyphenyl]...)
Affinity DataIC50: 752nMAssay Description:Displacement of [125I]IL8 from CXCR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193976(1-[4-chloro-3-({3-[(2R,6S)-2,6-dimethylmorpholin-4...)
Affinity DataIC50: 1.08E+3nMAssay Description:Displacement of [125I]IL8 from CXCR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193974(6-chloro-3-({(cyanoimino)[(2-fluorophenyl)amino]me...)
Affinity DataIC50: 1.55E+3nMAssay Description:Displacement of [125I]IL8 from CXCR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193975(6-chloro-3-{[[(3-chloro-2-fluorophenyl)amino](cyan...)
Affinity DataIC50: 6.20E+3nMAssay Description:Displacement of [125I]IL8 from CXCR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193983(1-[4-chloro-3-(dimethylsulfamoyl)-2-hydroxyphenyl]...)
Affinity DataIC50: 7.29E+3nMAssay Description:Displacement of [125I]IL8 from CXCR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed