BDBM666396 US20240116946, Example 429

SMILES COc1ccc(C#N)c(c1)-c1cc2[nH]c(=O)n(-c3cncc4ccc(OC)cc34)c(=O)c2cc1F

InChI Key InChIKey=IZHMYYBKBYNFPV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 666396   

TargetReplicase polyprotein 1a(2019-nCoV)
Gilead Sciences

US Patent
LigandPNGBDBM666396(US20240116946, Example 429)
Affinity DataIC50: 2.83nMAssay Description:This biochemical assay measured small molecule inhibitor IC50 values against recombinant SARS-CoV-2 Main protease (Mpro). Compounds from 100 μM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent