BDBM527020 US11186582, Example 274

SMILES Cc1cc([C@H]2CN(CC(F)(F)C2)C(=O)c2cc(Br)cc(Br)c2)n2ncnc2n1

InChI Key InChIKey=RFMFZFLZZZGIHE-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 527020   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Dart Neuroscience (Cayman)

US Patent

LigandBDBM527020(US11186582, Example 274)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/10/2022
Entry Details
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