BDBM50336920 3-chloro-N-(4-chlorophenyl)-5-(1,4-dimethyl-1H-imidazol-2-yl)pyridin-2-amine::CHEMBL1672438

SMILES Cc1cn(C)c(n1)-c1cnc(Nc2ccc(Cl)cc2)c(Cl)c1

InChI Key InChIKey=GXRSOTZPZCTLQG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336920   

TargetMetabotropic glutamate receptor 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336920(3-chloro-N-(4-chlorophenyl)-5-(1,4-dimethyl-1H-imi...)
Affinity DataIC50: 2.90E+3nMAssay Description:Antagonist activity at human mGlu5 receptor assessed as inhibition of glutamate-induced calcium flux by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed