BDBM50272315 CHEMBL524680::N-(3-Chloro-4-(trifluoromethyl)phenyl)-3-(3-(2-chloro-4-fluo-rophenyl)-1,2,4-oxadiazol-5-yl)propanamide

SMILES Fc1ccc(-c2noc(CCC(=O)Nc3ccc(c(Cl)c3)C(F)(F)F)n2)c(Cl)c1

InChI Key InChIKey=WLVORWCZCJGRGP-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50272315   

TargetCannabinoid receptor 2(Rat)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272315(N-(3-Chloro-4-(trifluoromethyl)phenyl)-3-(3-(2-chl...)
Affinity DataEC50:  79nMAssay Description:Agonist activity at rat recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272315(N-(3-Chloro-4-(trifluoromethyl)phenyl)-3-(3-(2-chl...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272315(N-(3-Chloro-4-(trifluoromethyl)phenyl)-3-(3-(2-chl...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272315(N-(3-Chloro-4-(trifluoromethyl)phenyl)-3-(3-(2-chl...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272315(N-(3-Chloro-4-(trifluoromethyl)phenyl)-3-(3-(2-chl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CB1 receptor expressed in Sf9 cells by GTP-europium binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272315(N-(3-Chloro-4-(trifluoromethyl)phenyl)-3-(3-(2-chl...)
Affinity DataEC50:  62nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in Sf9 cells by GTP-europium binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed