BDBM50270787 CHEMBL509774::NSFCRGRPGHFGGCYLF

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N4CCC[C@H]4C(=O)NCC(=O)N[C@@H](Cc5cnc[nH]5)C(=O)N[C@@H](Cc6ccccc6)C(=O)NCC(=O)NCC(=O)N2)C(=O)N[C@@H](Cc7ccccc7)C(O)=O

InChI Key InChIKey=DXRJJIPQJUARAV-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50270787   

TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50270787(NSFCRGRPGHFGGCYLF | CHEMBL509774)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human IgG binding to soluble human FcRn by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50270787(NSFCRGRPGHFGGCYLF | CHEMBL509774)
Affinity DataKd:  9.40E+3nMpH: 6.0Assay Description:Binding affinity to human FcRn at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50270787(NSFCRGRPGHFGGCYLF | CHEMBL509774)
Affinity DataKd:  9.30E+4nMpH: 7.4Assay Description:Binding affinity to human FcRn at pH 7.4 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed