BDBM50243560 CHEMBL4102969

SMILES Cc1c(nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OCc2ccccc2)cc1)C(=O)NN1CCCCC1

InChI Key InChIKey=NEDNEEPZMHBIAC-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50243560   

TargetCannabinoid receptor 1(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50243560(CHEMBL4102969)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at recombinant human CB1 receptor expressed in HEK293 cell membranes assessed as inhibition of CP55940-induced [35S]GTPgammaS bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2019
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50243560(CHEMBL4102969)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at recombinant human CB1 receptor expressed in HEK293 cell membranes assessed as inhibition of CP55940-induced [35S]GTPgammaS bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2019
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50243560(CHEMBL4102969)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in beta-galactosidase expressing CHOK1 cell membranes after 60 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2019
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50243560(CHEMBL4102969)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in beta-galactosidase expressing CHOK1 cell membranes after 60 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2019
Entry Details Article
PubMed