BDBM396411 3-[5-Chloro-2-(4-chloro-benzyloxy)-phenoxy]-azetidine::US9981909, Example 36

SMILES Clc1ccc(COc2ccc(Cl)cc2OC2CNC2)cc1

InChI Key InChIKey=AGLUMPCTWBGTIY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 396411   

Target5-hydroxytryptamine receptor 7(Rat)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396411BDBM396411(US9981909, Example 36 | 3-[5-Chloro-2-(4-chloro-be...)
Affinity DataKi:  15nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396411BDBM396411(US9981909, Example 36 | 3-[5-Chloro-2-(4-chloro-be...)
Affinity DataKi:  36nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent