BDBM381314 4-chloro-1-isopropyl-3-methyl-N- (4-(trifluoromethyl)phenyl)-1H- pyrazolo[3,4-b]pyridine-5- carboxamide::US10272074, Example 147

SMILES CC(C)n1nc(C)c2c(Cl)c(cnc12)C(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=NINVGNYBLRORJU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 381314   

TargetGlucocorticoid receptor(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM381314(4-chloro-1-isopropyl-3-methyl-N- (4-(trifluorometh...)
Affinity DataIC50: 50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
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