BDBM350551 1-(4-acetylphenyl)-3-{3-(4- cyanophenyl)-2-[2-(1H- imidazol-4-yl)ethyl]-1-oxo- 1,2,3,4-tetrahydroisoquinolin- 7-yl}urea::US10208071, Compound 13::US10434112, Compound 13::US10799518, Compound 13

SMILES CC(=O)c1ccc(NC(=O)Nc2ccc3CC(N(CCc4c[nH]cn4)C(=O)c3c2)c2ccc(cc2)C#N)cc1

InChI Key InChIKey=RLPOHZHEPHEMIA-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 350551   

TargetN-formyl peptide receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM350551(1-(4-acetylphenyl)-3-{3-(4- cyanophenyl)-2-[2-(1H-...)
Affinity DataEC50:  1.10E+4nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent

TargetN-formyl peptide receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM350551(1-(4-acetylphenyl)-3-{3-(4- cyanophenyl)-2-[2-(1H-...)
Affinity DataEC50:  11nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
Go to US Patent

TargetN-formyl peptide receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM350551(1-(4-acetylphenyl)-3-{3-(4- cyanophenyl)-2-[2-(1H-...)
Affinity DataEC50:  11nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent