BDBM209098 US9266877, 44

SMILES CN(C)CCCNc1ccc(Cn2cc(cn2)-c2ccc(nc2C(O)=O)N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)cc1[N+]([O-])=O

InChI Key InChIKey=SWGHOHOEWIDJCI-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209098   

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209098(US9266877, 44)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandPNGBDBM209098(US9266877, 44)
Affinity DataKi:  17nM ΔG°:  -10.6kcal/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent