BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Date of publication	Date in BindingDB	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID	PubChem SID	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence 1	PDB ID(s) of Target Chain 1	UniProt (SwissProt) Recommended Name of Target Chain 1	UniProt (SwissProt) Entry Name of Target Chain 1	UniProt (SwissProt) Primary ID of Target Chain 1	UniProt (SwissProt) Secondary ID(s) of Target Chain 1	UniProt (SwissProt) Alternative ID(s) of Target Chain 1	UniProt (TrEMBL) Submitted Name of Target Chain 1	UniProt (TrEMBL) Entry Name of Target Chain 1	UniProt (TrEMBL) Primary ID of Target Chain 1	UniProt (TrEMBL) Secondary ID(s) of Target Chain 1	UniProt (TrEMBL) Alternative ID(s) of Target Chain 1	BindingDB Target Chain Sequence 2	PDB ID(s) of Target Chain 2	UniProt (SwissProt) Recommended Name of Target Chain 2	UniProt (SwissProt) Entry Name of Target Chain 2	UniProt (SwissProt) Primary ID of Target Chain 2	UniProt (SwissProt) Secondary ID(s) of Target Chain 2	UniProt (SwissProt) Alternative ID(s) of Target Chain 2	UniProt (TrEMBL) Submitted Name of Target Chain 2	UniProt (TrEMBL) Entry Name of Target Chain 2	UniProt (TrEMBL) Primary ID of Target Chain 2	UniProt (TrEMBL) Secondary ID(s) of Target Chain 2	UniProt (TrEMBL) Alternative ID(s) of Target Chain 2	BindingDB Target Chain Sequence 3	PDB ID(s) of Target Chain 3	UniProt (SwissProt) Recommended Name of Target Chain 3	UniProt (SwissProt) Entry Name of Target Chain 3	UniProt (SwissProt) Primary ID of Target Chain 3	UniProt (SwissProt) Secondary ID(s) of Target Chain 3	UniProt (SwissProt) Alternative ID(s) of Target Chain 3	UniProt (TrEMBL) Submitted Name of Target Chain 3	UniProt (TrEMBL) Entry Name of Target Chain 3	UniProt (TrEMBL) Primary ID of Target Chain 3	UniProt (TrEMBL) Secondary ID(s) of Target Chain 3	UniProt (TrEMBL) Alternative ID(s) of Target Chain 3	BindingDB Target Chain Sequence 4	PDB ID(s) of Target Chain 4	UniProt (SwissProt) Recommended Name of Target Chain 4	UniProt (SwissProt) Entry Name of Target Chain 4	UniProt (SwissProt) Primary ID of Target Chain 4	UniProt (SwissProt) Secondary ID(s) of Target Chain 4	UniProt (SwissProt) Alternative ID(s) of Target Chain 4	UniProt (TrEMBL) Submitted Name of Target Chain 4	UniProt (TrEMBL) Entry Name of Target Chain 4	UniProt (TrEMBL) Primary ID of Target Chain 4	UniProt (TrEMBL) Secondary ID(s) of Target Chain 4	UniProt (TrEMBL) Alternative ID(s) of Target Chain 4	BindingDB Target Chain Sequence 5	PDB ID(s) of Target Chain 5	UniProt (SwissProt) Recommended Name of Target Chain 5	UniProt (SwissProt) Entry Name of Target Chain 5	UniProt (SwissProt) Primary ID of Target Chain 5	UniProt (SwissProt) Secondary ID(s) of Target Chain 5	UniProt (SwissProt) Alternative ID(s) of Target Chain 5	UniProt (TrEMBL) Submitted Name of Target Chain 5	UniProt (TrEMBL) Entry Name of Target Chain 5	UniProt (TrEMBL) Primary ID of Target Chain 5	UniProt (TrEMBL) Secondary ID(s) of Target Chain 5	UniProt (TrEMBL) Alternative ID(s) of Target Chain 5	BindingDB Target Chain Sequence 6	PDB ID(s) of Target Chain 6	UniProt (SwissProt) Recommended Name of Target Chain 6	UniProt (SwissProt) Entry Name of Target Chain 6	UniProt (SwissProt) Primary ID of Target Chain 6	UniProt (SwissProt) Secondary ID(s) of Target Chain 6	UniProt (SwissProt) Alternative ID(s) of Target Chain 6	UniProt (TrEMBL) Submitted Name of Target Chain 6	UniProt (TrEMBL) Entry Name of Target Chain 6	UniProt (TrEMBL) Primary ID of Target Chain 6	UniProt (TrEMBL) Secondary ID(s) of Target Chain 6	UniProt (TrEMBL) Alternative ID(s) of Target Chain 6	BindingDB Target Chain Sequence 7	PDB ID(s) of Target Chain 7	UniProt (SwissProt) Recommended Name of Target Chain 7	UniProt (SwissProt) Entry Name of Target Chain 7	UniProt (SwissProt) Primary ID of Target Chain 7	UniProt (SwissProt) Secondary ID(s) of Target Chain 7	UniProt (SwissProt) Alternative ID(s) of Target Chain 7	UniProt (TrEMBL) Submitted Name of Target Chain 7	UniProt (TrEMBL) Entry Name of Target Chain 7	UniProt (TrEMBL) Primary ID of Target Chain 7	UniProt (TrEMBL) Secondary ID(s) of Target Chain 7	UniProt (TrEMBL) Alternative ID(s) of Target Chain 7	BindingDB Target Chain Sequence 8	PDB ID(s) of Target Chain 8	UniProt (SwissProt) Recommended Name of Target Chain 8	UniProt (SwissProt) Entry Name of Target Chain 8	UniProt (SwissProt) Primary ID of Target Chain 8	UniProt (SwissProt) Secondary ID(s) of Target Chain 8	UniProt (SwissProt) Alternative ID(s) of Target Chain 8	UniProt (TrEMBL) Submitted Name of Target Chain 8	UniProt (TrEMBL) Entry Name of Target Chain 8	UniProt (TrEMBL) Primary ID of Target Chain 8	UniProt (TrEMBL) Secondary ID(s) of Target Chain 8	UniProt (TrEMBL) Alternative ID(s) of Target Chain 8	BindingDB Target Chain Sequence 9	PDB ID(s) of Target Chain 9	UniProt (SwissProt) Recommended Name of Target Chain 9	UniProt (SwissProt) Entry Name of Target Chain 9	UniProt (SwissProt) Primary ID of Target Chain 9	UniProt (SwissProt) Secondary ID(s) of Target Chain 9	UniProt (SwissProt) Alternative ID(s) of Target Chain 9	UniProt (TrEMBL) Submitted Name of Target Chain 9	UniProt (TrEMBL) Entry Name of Target Chain 9	UniProt (TrEMBL) Primary ID of Target Chain 9	UniProt (TrEMBL) Secondary ID(s) of Target Chain 9	UniProt (TrEMBL) Alternative ID(s) of Target Chain 9	BindingDB Target Chain Sequence 10	PDB ID(s) of Target Chain 10	UniProt (SwissProt) Recommended Name of Target Chain 10	UniProt (SwissProt) Entry Name of Target Chain 10	UniProt (SwissProt) Primary ID of Target Chain 10	UniProt (SwissProt) Secondary ID(s) of Target Chain 10	UniProt (SwissProt) Alternative ID(s) of Target Chain 10	UniProt (TrEMBL) Submitted Name of Target Chain 10	UniProt (TrEMBL) Entry Name of Target Chain 10	UniProt (TrEMBL) Primary ID of Target Chain 10	UniProt (TrEMBL) Secondary ID(s) of Target Chain 10	UniProt (TrEMBL) Alternative ID(s) of Target Chain 10	BindingDB Target Chain Sequence 11	PDB ID(s) of Target Chain 11	UniProt (SwissProt) Recommended Name of Target Chain 11	UniProt (SwissProt) Entry Name of Target Chain 11	UniProt (SwissProt) Primary ID of Target Chain 11	UniProt (SwissProt) Secondary ID(s) of Target Chain 11	UniProt (SwissProt) Alternative ID(s) of Target Chain 11	UniProt (TrEMBL) Submitted Name of Target Chain 11	UniProt (TrEMBL) Entry Name of Target Chain 11	UniProt (TrEMBL) Primary ID of Target Chain 11	UniProt (TrEMBL) Secondary ID(s) of Target Chain 11	UniProt (TrEMBL) Alternative ID(s) of Target Chain 11	BindingDB Target Chain Sequence 12	PDB ID(s) of Target Chain 12	UniProt (SwissProt) Recommended Name of Target Chain 12	UniProt (SwissProt) Entry Name of Target Chain 12	UniProt (SwissProt) Primary ID of Target Chain 12	UniProt (SwissProt) Secondary ID(s) of Target Chain 12	UniProt (SwissProt) Alternative ID(s) of Target Chain 12	UniProt (TrEMBL) Submitted Name of Target Chain 12	UniProt (TrEMBL) Entry Name of Target Chain 12	UniProt (TrEMBL) Primary ID of Target Chain 12	UniProt (TrEMBL) Secondary ID(s) of Target Chain 12	UniProt (TrEMBL) Alternative ID(s) of Target Chain 12	BindingDB Target Chain Sequence 13	PDB ID(s) of Target Chain 13	UniProt (SwissProt) Recommended Name of Target Chain 13	UniProt (SwissProt) Entry Name of Target Chain 13	UniProt (SwissProt) Primary ID of Target Chain 13	UniProt (SwissProt) Secondary ID(s) of Target Chain 13	UniProt (SwissProt) Alternative ID(s) of Target Chain 13	UniProt (TrEMBL) Submitted Name of Target Chain 13	UniProt (TrEMBL) Entry Name of Target Chain 13	UniProt (TrEMBL) Primary ID of Target Chain 13	UniProt (TrEMBL) Secondary ID(s) of Target Chain 13	UniProt (TrEMBL) Alternative ID(s) of Target Chain 13	BindingDB Target Chain Sequence 14	PDB ID(s) of Target Chain 14	UniProt (SwissProt) Recommended Name of Target Chain 14	UniProt (SwissProt) Entry Name of Target Chain 14	UniProt (SwissProt) Primary ID of Target Chain 14	UniProt (SwissProt) Secondary ID(s) of Target Chain 14	UniProt (SwissProt) Alternative ID(s) of Target Chain 14	UniProt (TrEMBL) Submitted Name of Target Chain 14	UniProt (TrEMBL) Entry Name of Target Chain 14	UniProt (TrEMBL) Primary ID of Target Chain 14	UniProt (TrEMBL) Secondary ID(s) of Target Chain 14	UniProt (TrEMBL) Alternative ID(s) of Target Chain 14	BindingDB Target Chain Sequence 15	PDB ID(s) of Target Chain 15	UniProt (SwissProt) Recommended Name of Target Chain 15	UniProt (SwissProt) Entry Name of Target Chain 15	UniProt (SwissProt) Primary ID of Target Chain 15	UniProt (SwissProt) Secondary ID(s) of Target Chain 15	UniProt (SwissProt) Alternative ID(s) of Target Chain 15	UniProt (TrEMBL) Submitted Name of Target Chain 15	UniProt (TrEMBL) Entry Name of Target Chain 15	UniProt (TrEMBL) Primary ID of Target Chain 15	UniProt (TrEMBL) Secondary ID(s) of Target Chain 15	UniProt (TrEMBL) Alternative ID(s) of Target Chain 15	BindingDB Target Chain Sequence 16	PDB ID(s) of Target Chain 16	UniProt (SwissProt) Recommended Name of Target Chain 16	UniProt (SwissProt) Entry Name of Target Chain 16	UniProt (SwissProt) Primary ID of Target Chain 16	UniProt (SwissProt) Secondary ID(s) of Target Chain 16	UniProt (SwissProt) Alternative ID(s) of Target Chain 16	UniProt (TrEMBL) Submitted Name of Target Chain 16	UniProt (TrEMBL) Entry Name of Target Chain 16	UniProt (TrEMBL) Primary ID of Target Chain 16	UniProt (TrEMBL) Secondary ID(s) of Target Chain 16	UniProt (TrEMBL) Alternative ID(s) of Target Chain 16	BindingDB Target Chain Sequence 17	PDB ID(s) of Target Chain 17	UniProt (SwissProt) Recommended Name of Target Chain 17	UniProt (SwissProt) Entry Name of Target Chain 17	UniProt (SwissProt) Primary ID of Target Chain 17	UniProt (SwissProt) Secondary ID(s) of Target Chain 17	UniProt (SwissProt) Alternative ID(s) of Target Chain 17	UniProt (TrEMBL) Submitted Name of Target Chain 17	UniProt (TrEMBL) Entry Name of Target Chain 17	UniProt (TrEMBL) Primary ID of Target Chain 17	UniProt (TrEMBL) Secondary ID(s) of Target Chain 17	UniProt (TrEMBL) Alternative ID(s) of Target Chain 17	BindingDB Target Chain Sequence 18	PDB ID(s) of Target Chain 18	UniProt (SwissProt) Recommended Name of Target Chain 18	UniProt (SwissProt) Entry Name of Target Chain 18	UniProt (SwissProt) Primary ID of Target Chain 18	UniProt (SwissProt) Secondary ID(s) of Target Chain 18	UniProt (SwissProt) Alternative ID(s) of Target Chain 18	UniProt (TrEMBL) Submitted Name of Target Chain 18	UniProt (TrEMBL) Entry Name of Target Chain 18	UniProt (TrEMBL) Primary ID of Target Chain 18	UniProt (TrEMBL) Secondary ID(s) of Target Chain 18	UniProt (TrEMBL) Alternative ID(s) of Target Chain 18	BindingDB Target Chain Sequence 19	PDB ID(s) of Target Chain 19	UniProt (SwissProt) Recommended Name of Target Chain 19	UniProt (SwissProt) Entry Name of Target Chain 19	UniProt (SwissProt) Primary ID of Target Chain 19	UniProt (SwissProt) Secondary ID(s) of Target Chain 19	UniProt (SwissProt) Alternative ID(s) of Target Chain 19	UniProt (TrEMBL) Submitted Name of Target Chain 19	UniProt (TrEMBL) Entry Name of Target Chain 19	UniProt (TrEMBL) Primary ID of Target Chain 19	UniProt (TrEMBL) Secondary ID(s) of Target Chain 19	UniProt (TrEMBL) Alternative ID(s) of Target Chain 19	BindingDB Target Chain Sequence 20	PDB ID(s) of Target Chain 20	UniProt (SwissProt) Recommended Name of Target Chain 20	UniProt (SwissProt) Entry Name of Target Chain 20	UniProt (SwissProt) Primary ID of Target Chain 20	UniProt (SwissProt) Secondary ID(s) of Target Chain 20	UniProt (SwissProt) Alternative ID(s) of Target Chain 20	UniProt (TrEMBL) Submitted Name of Target Chain 20	UniProt (TrEMBL) Entry Name of Target Chain 20	UniProt (TrEMBL) Primary ID of Target Chain 20	UniProt (TrEMBL) Secondary ID(s) of Target Chain 20	UniProt (TrEMBL) Alternative ID(s) of Target Chain 20	BindingDB Target Chain Sequence 21	PDB ID(s) of Target Chain 21	UniProt (SwissProt) Recommended Name of Target Chain 21	UniProt (SwissProt) Entry Name of Target Chain 21	UniProt (SwissProt) Primary ID of Target Chain 21	UniProt (SwissProt) Secondary ID(s) of Target Chain 21	UniProt (SwissProt) Alternative ID(s) of Target Chain 21	UniProt (TrEMBL) Submitted Name of Target Chain 21	UniProt (TrEMBL) Entry Name of Target Chain 21	UniProt (TrEMBL) Primary ID of Target Chain 21	UniProt (TrEMBL) Secondary ID(s) of Target Chain 21	UniProt (TrEMBL) Alternative ID(s) of Target Chain 21	BindingDB Target Chain Sequence 22	PDB ID(s) of Target Chain 22	UniProt (SwissProt) Recommended Name of Target Chain 22	UniProt (SwissProt) Entry Name of Target Chain 22	UniProt (SwissProt) Primary ID of Target Chain 22	UniProt (SwissProt) Secondary ID(s) of Target Chain 22	UniProt (SwissProt) Alternative ID(s) of Target Chain 22	UniProt (TrEMBL) Submitted Name of Target Chain 22	UniProt (TrEMBL) Entry Name of Target Chain 22	UniProt (TrEMBL) Primary ID of Target Chain 22	UniProt (TrEMBL) Secondary ID(s) of Target Chain 22	UniProt (TrEMBL) Alternative ID(s) of Target Chain 22	BindingDB Target Chain Sequence 23	PDB ID(s) of Target Chain 23	UniProt (SwissProt) Recommended Name of Target Chain 23	UniProt (SwissProt) Entry Name of Target Chain 23	UniProt (SwissProt) Primary ID of Target Chain 23	UniProt (SwissProt) Secondary ID(s) of Target Chain 23	UniProt (SwissProt) Alternative ID(s) of Target Chain 23	UniProt (TrEMBL) Submitted Name of Target Chain 23	UniProt (TrEMBL) Entry Name of Target Chain 23	UniProt (TrEMBL) Primary ID of Target Chain 23	UniProt (TrEMBL) Secondary ID(s) of Target Chain 23	UniProt (TrEMBL) Alternative ID(s) of Target Chain 23	BindingDB Target Chain Sequence 24	PDB ID(s) of Target Chain 24	UniProt (SwissProt) Recommended Name of Target Chain 24	UniProt (SwissProt) Entry Name of Target Chain 24	UniProt (SwissProt) Primary ID of Target Chain 24	UniProt (SwissProt) Secondary ID(s) of Target Chain 24	UniProt (SwissProt) Alternative ID(s) of Target Chain 24	UniProt (TrEMBL) Submitted Name of Target Chain 24	UniProt (TrEMBL) Entry Name of Target Chain 24	UniProt (TrEMBL) Primary ID of Target Chain 24	UniProt (TrEMBL) Secondary ID(s) of Target Chain 24	UniProt (TrEMBL) Alternative ID(s) of Target Chain 24	BindingDB Target Chain Sequence 25	PDB ID(s) of Target Chain 25	UniProt (SwissProt) Recommended Name of Target Chain 25	UniProt (SwissProt) Entry Name of Target Chain 25	UniProt (SwissProt) Primary ID of Target Chain 25	UniProt (SwissProt) Secondary ID(s) of Target Chain 25	UniProt (SwissProt) Alternative ID(s) of Target Chain 25	UniProt (TrEMBL) Submitted Name of Target Chain 25	UniProt (TrEMBL) Entry Name of Target Chain 25	UniProt (TrEMBL) Primary ID of Target Chain 25	UniProt (TrEMBL) Secondary ID(s) of Target Chain 25	UniProt (TrEMBL) Alternative ID(s) of Target Chain 25	BindingDB Target Chain Sequence 26	PDB ID(s) of Target Chain 26	UniProt (SwissProt) Recommended Name of Target Chain 26	UniProt (SwissProt) Entry Name of Target Chain 26	UniProt (SwissProt) Primary ID of Target Chain 26	UniProt (SwissProt) Secondary ID(s) of Target Chain 26	UniProt (SwissProt) Alternative ID(s) of Target Chain 26	UniProt (TrEMBL) Submitted Name of Target Chain 26	UniProt (TrEMBL) Entry Name of Target Chain 26	UniProt (TrEMBL) Primary ID of Target Chain 26	UniProt (TrEMBL) Secondary ID(s) of Target Chain 26	UniProt (TrEMBL) Alternative ID(s) of Target Chain 26	BindingDB Target Chain Sequence 27	PDB ID(s) of Target Chain 27	UniProt (SwissProt) Recommended Name of Target Chain 27	UniProt (SwissProt) Entry Name of Target Chain 27	UniProt (SwissProt) Primary ID of Target Chain 27	UniProt (SwissProt) Secondary ID(s) of Target Chain 27	UniProt (SwissProt) Alternative ID(s) of Target Chain 27	UniProt (TrEMBL) Submitted Name of Target Chain 27	UniProt (TrEMBL) Entry Name of Target Chain 27	UniProt (TrEMBL) Primary ID of Target Chain 27	UniProt (TrEMBL) Secondary ID(s) of Target Chain 27	UniProt (TrEMBL) Alternative ID(s) of Target Chain 27	BindingDB Target Chain Sequence 28	PDB ID(s) of Target Chain 28	UniProt (SwissProt) Recommended Name of Target Chain 28	UniProt (SwissProt) Entry Name of Target Chain 28	UniProt (SwissProt) Primary ID of Target Chain 28	UniProt (SwissProt) Secondary ID(s) of Target Chain 28	UniProt (SwissProt) Alternative ID(s) of Target Chain 28	UniProt (TrEMBL) Submitted Name of Target Chain 28	UniProt (TrEMBL) Entry Name of Target Chain 28	UniProt (TrEMBL) Primary ID of Target Chain 28	UniProt (TrEMBL) Secondary ID(s) of Target Chain 28	UniProt (TrEMBL) Alternative ID(s) of Target Chain 28	BindingDB Target Chain Sequence 29	PDB ID(s) of Target Chain 29	UniProt (SwissProt) Recommended Name of Target Chain 29	UniProt (SwissProt) Entry Name of Target Chain 29	UniProt (SwissProt) Primary ID of Target Chain 29	UniProt (SwissProt) Secondary ID(s) of Target Chain 29	UniProt (SwissProt) Alternative ID(s) of Target Chain 29	UniProt (TrEMBL) Submitted Name of Target Chain 29	UniProt (TrEMBL) Entry Name of Target Chain 29	UniProt (TrEMBL) Primary ID of Target Chain 29	UniProt (TrEMBL) Secondary ID(s) of Target Chain 29	UniProt (TrEMBL) Alternative ID(s) of Target Chain 29	BindingDB Target Chain Sequence 30	PDB ID(s) of Target Chain 30	UniProt (SwissProt) Recommended Name of Target Chain 30	UniProt (SwissProt) Entry Name of Target Chain 30	UniProt (SwissProt) Primary ID of Target Chain 30	UniProt (SwissProt) Secondary ID(s) of Target Chain 30	UniProt (SwissProt) Alternative ID(s) of Target Chain 30	UniProt (TrEMBL) Submitted Name of Target Chain 30	UniProt (TrEMBL) Entry Name of Target Chain 30	UniProt (TrEMBL) Primary ID of Target Chain 30	UniProt (TrEMBL) Secondary ID(s) of Target Chain 30	UniProt (TrEMBL) Alternative ID(s) of Target Chain 30	BindingDB Target Chain Sequence 31	PDB ID(s) of Target Chain 31	UniProt (SwissProt) Recommended Name of Target Chain 31	UniProt (SwissProt) Entry Name of Target Chain 31	UniProt (SwissProt) Primary ID of Target Chain 31	UniProt (SwissProt) Secondary ID(s) of Target Chain 31	UniProt (SwissProt) Alternative ID(s) of Target Chain 31	UniProt (TrEMBL) Submitted Name of Target Chain 31	UniProt (TrEMBL) Entry Name of Target Chain 31	UniProt (TrEMBL) Primary ID of Target Chain 31	UniProt (TrEMBL) Secondary ID(s) of Target Chain 31	UniProt (TrEMBL) Alternative ID(s) of Target Chain 31	BindingDB Target Chain Sequence 32	PDB ID(s) of Target Chain 32	UniProt (SwissProt) Recommended Name of Target Chain 32	UniProt (SwissProt) Entry Name of Target Chain 32	UniProt (SwissProt) Primary ID of Target Chain 32	UniProt (SwissProt) Secondary ID(s) of Target Chain 32	UniProt (SwissProt) Alternative ID(s) of Target Chain 32	UniProt (TrEMBL) Submitted Name of Target Chain 32	UniProt (TrEMBL) Entry Name of Target Chain 32	UniProt (TrEMBL) Primary ID of Target Chain 32	UniProt (TrEMBL) Secondary ID(s) of Target Chain 32	UniProt (TrEMBL) Alternative ID(s) of Target Chain 32	BindingDB Target Chain Sequence 33	PDB ID(s) of Target Chain 33	UniProt (SwissProt) Recommended Name of Target Chain 33	UniProt (SwissProt) Entry Name of Target Chain 33	UniProt (SwissProt) Primary ID of Target Chain 33	UniProt (SwissProt) Secondary ID(s) of Target Chain 33	UniProt (SwissProt) Alternative ID(s) of Target Chain 33	UniProt (TrEMBL) Submitted Name of Target Chain 33	UniProt (TrEMBL) Entry Name of Target Chain 33	UniProt (TrEMBL) Primary ID of Target Chain 33	UniProt (TrEMBL) Secondary ID(s) of Target Chain 33	UniProt (TrEMBL) Alternative ID(s) of Target Chain 33	BindingDB Target Chain Sequence 34	PDB ID(s) of Target Chain 34	UniProt (SwissProt) Recommended Name of Target Chain 34	UniProt (SwissProt) Entry Name of Target Chain 34	UniProt (SwissProt) Primary ID of Target Chain 34	UniProt (SwissProt) Secondary ID(s) of Target Chain 34	UniProt (SwissProt) Alternative ID(s) of Target Chain 34	UniProt (TrEMBL) Submitted Name of Target Chain 34	UniProt (TrEMBL) Entry Name of Target Chain 34	UniProt (TrEMBL) Primary ID of Target Chain 34	UniProt (TrEMBL) Secondary ID(s) of Target Chain 34	UniProt (TrEMBL) Alternative ID(s) of Target Chain 34	BindingDB Target Chain Sequence 35	PDB ID(s) of Target Chain 35	UniProt (SwissProt) Recommended Name of Target Chain 35	UniProt (SwissProt) Entry Name of Target Chain 35	UniProt (SwissProt) Primary ID of Target Chain 35	UniProt (SwissProt) Secondary ID(s) of Target Chain 35	UniProt (SwissProt) Alternative ID(s) of Target Chain 35	UniProt (TrEMBL) Submitted Name of Target Chain 35	UniProt (TrEMBL) Entry Name of Target Chain 35	UniProt (TrEMBL) Primary ID of Target Chain 35	UniProt (TrEMBL) Secondary ID(s) of Target Chain 35	UniProt (TrEMBL) Alternative ID(s) of Target Chain 35	BindingDB Target Chain Sequence 36	PDB ID(s) of Target Chain 36	UniProt (SwissProt) Recommended Name of Target Chain 36	UniProt (SwissProt) Entry Name of Target Chain 36	UniProt (SwissProt) Primary ID of Target Chain 36	UniProt (SwissProt) Secondary ID(s) of Target Chain 36	UniProt (SwissProt) Alternative ID(s) of Target Chain 36	UniProt (TrEMBL) Submitted Name of Target Chain 36	UniProt (TrEMBL) Entry Name of Target Chain 36	UniProt (TrEMBL) Primary ID of Target Chain 36	UniProt (TrEMBL) Secondary ID(s) of Target Chain 36	UniProt (TrEMBL) Alternative ID(s) of Target Chain 36	BindingDB Target Chain Sequence 37	PDB ID(s) of Target Chain 37	UniProt (SwissProt) Recommended Name of Target Chain 37	UniProt (SwissProt) Entry Name of Target Chain 37	UniProt (SwissProt) Primary ID of Target Chain 37	UniProt (SwissProt) Secondary ID(s) of Target Chain 37	UniProt (SwissProt) Alternative ID(s) of Target Chain 37	UniProt (TrEMBL) Submitted Name of Target Chain 37	UniProt (TrEMBL) Entry Name of Target Chain 37	UniProt (TrEMBL) Primary ID of Target Chain 37	UniProt (TrEMBL) Secondary ID(s) of Target Chain 37	UniProt (TrEMBL) Alternative ID(s) of Target Chain 37	BindingDB Target Chain Sequence 38	PDB ID(s) of Target Chain 38	UniProt (SwissProt) Recommended Name of Target Chain 38	UniProt (SwissProt) Entry Name of Target Chain 38	UniProt (SwissProt) Primary ID of Target Chain 38	UniProt (SwissProt) Secondary ID(s) of Target Chain 38	UniProt (SwissProt) Alternative ID(s) of Target Chain 38	UniProt (TrEMBL) Submitted Name of Target Chain 38	UniProt (TrEMBL) Entry Name of Target Chain 38	UniProt (TrEMBL) Primary ID of Target Chain 38	UniProt (TrEMBL) Secondary ID(s) of Target Chain 38	UniProt (TrEMBL) Alternative ID(s) of Target Chain 38	BindingDB Target Chain Sequence 39	PDB ID(s) of Target Chain 39	UniProt (SwissProt) Recommended Name of Target Chain 39	UniProt (SwissProt) Entry Name of Target Chain 39	UniProt (SwissProt) Primary ID of Target Chain 39	UniProt (SwissProt) Secondary ID(s) of Target Chain 39	UniProt (SwissProt) Alternative ID(s) of Target Chain 39	UniProt (TrEMBL) Submitted Name of Target Chain 39	UniProt (TrEMBL) Entry Name of Target Chain 39	UniProt (TrEMBL) Primary ID of Target Chain 39	UniProt (TrEMBL) Secondary ID(s) of Target Chain 39	UniProt (TrEMBL) Alternative ID(s) of Target Chain 39	BindingDB Target Chain Sequence 40	PDB ID(s) of Target Chain 40	UniProt (SwissProt) Recommended Name of Target Chain 40	UniProt (SwissProt) Entry Name of Target Chain 40	UniProt (SwissProt) Primary ID of Target Chain 40	UniProt (SwissProt) Secondary ID(s) of Target Chain 40	UniProt (SwissProt) Alternative ID(s) of Target Chain 40	UniProt (TrEMBL) Submitted Name of Target Chain 40	UniProt (TrEMBL) Entry Name of Target Chain 40	UniProt (TrEMBL) Primary ID of Target Chain 40	UniProt (TrEMBL) Secondary ID(s) of Target Chain 40	UniProt (TrEMBL) Alternative ID(s) of Target Chain 40	BindingDB Target Chain Sequence 41	PDB ID(s) of Target Chain 41	UniProt (SwissProt) Recommended Name of Target Chain 41	UniProt (SwissProt) Entry Name of Target Chain 41	UniProt (SwissProt) Primary ID of Target Chain 41	UniProt (SwissProt) Secondary ID(s) of Target Chain 41	UniProt (SwissProt) Alternative ID(s) of Target Chain 41	UniProt (TrEMBL) Submitted Name of Target Chain 41	UniProt (TrEMBL) Entry Name of Target Chain 41	UniProt (TrEMBL) Primary ID of Target Chain 41	UniProt (TrEMBL) Secondary ID(s) of Target Chain 41	UniProt (TrEMBL) Alternative ID(s) of Target Chain 41	BindingDB Target Chain Sequence 42	PDB ID(s) of Target Chain 42	UniProt (SwissProt) Recommended Name of Target Chain 42	UniProt (SwissProt) Entry Name of Target Chain 42	UniProt (SwissProt) Primary ID of Target Chain 42	UniProt (SwissProt) Secondary ID(s) of Target Chain 42	UniProt (SwissProt) Alternative ID(s) of Target Chain 42	UniProt (TrEMBL) Submitted Name of Target Chain 42	UniProt (TrEMBL) Entry Name of Target Chain 42	UniProt (TrEMBL) Primary ID of Target Chain 42	UniProt (TrEMBL) Secondary ID(s) of Target Chain 42	UniProt (TrEMBL) Alternative ID(s) of Target Chain 42	BindingDB Target Chain Sequence 43	PDB ID(s) of Target Chain 43	UniProt (SwissProt) Recommended Name of Target Chain 43	UniProt (SwissProt) Entry Name of Target Chain 43	UniProt (SwissProt) Primary ID of Target Chain 43	UniProt (SwissProt) Secondary ID(s) of Target Chain 43	UniProt (SwissProt) Alternative ID(s) of Target Chain 43	UniProt (TrEMBL) Submitted Name of Target Chain 43	UniProt (TrEMBL) Entry Name of Target Chain 43	UniProt (TrEMBL) Primary ID of Target Chain 43	UniProt (TrEMBL) Secondary ID(s) of Target Chain 43	UniProt (TrEMBL) Alternative ID(s) of Target Chain 43	BindingDB Target Chain Sequence 44	PDB ID(s) of Target Chain 44	UniProt (SwissProt) Recommended Name of Target Chain 44	UniProt (SwissProt) Entry Name of Target Chain 44	UniProt (SwissProt) Primary ID of Target Chain 44	UniProt (SwissProt) Secondary ID(s) of Target Chain 44	UniProt (SwissProt) Alternative ID(s) of Target Chain 44	UniProt (TrEMBL) Submitted Name of Target Chain 44	UniProt (TrEMBL) Entry Name of Target Chain 44	UniProt (TrEMBL) Primary ID of Target Chain 44	UniProt (TrEMBL) Secondary ID(s) of Target Chain 44	UniProt (TrEMBL) Alternative ID(s) of Target Chain 44	BindingDB Target Chain Sequence 45	PDB ID(s) of Target Chain 45	UniProt (SwissProt) Recommended Name of Target Chain 45	UniProt (SwissProt) Entry Name of Target Chain 45	UniProt (SwissProt) Primary ID of Target Chain 45	UniProt (SwissProt) Secondary ID(s) of Target Chain 45	UniProt (SwissProt) Alternative ID(s) of Target Chain 45	UniProt (TrEMBL) Submitted Name of Target Chain 45	UniProt (TrEMBL) Entry Name of Target Chain 45	UniProt (TrEMBL) Primary ID of Target Chain 45	UniProt (TrEMBL) Secondary ID(s) of Target Chain 45	UniProt (TrEMBL) Alternative ID(s) of Target Chain 45	BindingDB Target Chain Sequence 46	PDB ID(s) of Target Chain 46	UniProt (SwissProt) Recommended Name of Target Chain 46	UniProt (SwissProt) Entry Name of Target Chain 46	UniProt (SwissProt) Primary ID of Target Chain 46	UniProt (SwissProt) Secondary ID(s) of Target Chain 46	UniProt (SwissProt) Alternative ID(s) of Target Chain 46	UniProt (TrEMBL) Submitted Name of Target Chain 46	UniProt (TrEMBL) Entry Name of Target Chain 46	UniProt (TrEMBL) Primary ID of Target Chain 46	UniProt (TrEMBL) Secondary ID(s) of Target Chain 46	UniProt (TrEMBL) Alternative ID(s) of Target Chain 46	BindingDB Target Chain Sequence 47	PDB ID(s) of Target Chain 47	UniProt (SwissProt) Recommended Name of Target Chain 47	UniProt (SwissProt) Entry Name of Target Chain 47	UniProt (SwissProt) Primary ID of Target Chain 47	UniProt (SwissProt) Secondary ID(s) of Target Chain 47	UniProt (SwissProt) Alternative ID(s) of Target Chain 47	UniProt (TrEMBL) Submitted Name of Target Chain 47	UniProt (TrEMBL) Entry Name of Target Chain 47	UniProt (TrEMBL) Primary ID of Target Chain 47	UniProt (TrEMBL) Secondary ID(s) of Target Chain 47	UniProt (TrEMBL) Alternative ID(s) of Target Chain 47	BindingDB Target Chain Sequence 48	PDB ID(s) of Target Chain 48	UniProt (SwissProt) Recommended Name of Target Chain 48	UniProt (SwissProt) Entry Name of Target Chain 48	UniProt (SwissProt) Primary ID of Target Chain 48	UniProt (SwissProt) Secondary ID(s) of Target Chain 48	UniProt (SwissProt) Alternative ID(s) of Target Chain 48	UniProt (TrEMBL) Submitted Name of Target Chain 48	UniProt (TrEMBL) Entry Name of Target Chain 48	UniProt (TrEMBL) Primary ID of Target Chain 48	UniProt (TrEMBL) Secondary ID(s) of Target Chain 48	UniProt (TrEMBL) Alternative ID(s) of Target Chain 48	BindingDB Target Chain Sequence 49	PDB ID(s) of Target Chain 49	UniProt (SwissProt) Recommended Name of Target Chain 49	UniProt (SwissProt) Entry Name of Target Chain 49	UniProt (SwissProt) Primary ID of Target Chain 49	UniProt (SwissProt) Secondary ID(s) of Target Chain 49	UniProt (SwissProt) Alternative ID(s) of Target Chain 49	UniProt (TrEMBL) Submitted Name of Target Chain 49	UniProt (TrEMBL) Entry Name of Target Chain 49	UniProt (TrEMBL) Primary ID of Target Chain 49	UniProt (TrEMBL) Secondary ID(s) of Target Chain 49	UniProt (TrEMBL) Alternative ID(s) of Target Chain 49	BindingDB Target Chain Sequence 50	PDB ID(s) of Target Chain 50	UniProt (SwissProt) Recommended Name of Target Chain 50	UniProt (SwissProt) Entry Name of Target Chain 50	UniProt (SwissProt) Primary ID of Target Chain 50	UniProt (SwissProt) Secondary ID(s) of Target Chain 50	UniProt (SwissProt) Alternative ID(s) of Target Chain 50	UniProt (TrEMBL) Submitted Name of Target Chain 50	UniProt (TrEMBL) Entry Name of Target Chain 50	UniProt (TrEMBL) Primary ID of Target Chain 50	UniProt (TrEMBL) Secondary ID(s) of Target Chain 50	UniProt (TrEMBL) Alternative ID(s) of Target Chain 50
1573449	CN[C@H](C)CN1CCC2C=C3C(CC2C1=O)N=C(c1cc2ccccc2n1CC1CC1)N3C			786033	US20250346592, Example 1	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786033	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786033&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185100	523968778							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573450	CN[C@H](C)CN1CCC2C=C3C(CC2C1=O)N=C(c1cc2ccccc2n1CC1CC1)N3C			786033	US20250346592, Example 1	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786033	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786033&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185100	523968778							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573451	CCN[C@H](C)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccccc2n1CC1CC1)n3C			786034	US20250346592, Example 2	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786034	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786034&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604215	523968779							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573452	C[C@H](CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccccc2n1CC1CC1)n3C)NCCF			786035	US20250346592, Example 3	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786035	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786035&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774279	523968780							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573453	C[C@H](CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccccc2n1CC1CC1)n3C)NCCF			786035	US20250346592, Example 3	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786035	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786035&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774279	523968780							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573454	CCCN[C@H](C)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccccc2n1CC1CC1)n3C			786036	US20250346592, Example 4	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786036	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786036&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774134	523968781							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573455	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccccc2n1CC1CC1)n3C			786037	US20250346592, Example 5	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786037	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786037&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344334	523968782							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573456	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccccc2n1CC1CC1)n3C			786037	US20250346592, Example 5	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786037	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786037&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344334	523968782							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573457	Cn1c(-c2cc3ccccc3n2CC2CC2)nc2cc3c(cc21)CCN(CC(C)(C)N)C3=O			786038	US20250346592, Example 6	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786038	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786038&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774165	523968783							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573458	Cn1c(-c2cc3ccccc3n2CC2CC2)nc2cc3c(cc21)CCN(CC(C)(C)N)C3=O			786038	US20250346592, Example 6	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786038	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786038&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774165	523968783							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573459	Cn1c(-c2cc3ccccc3n2CC2CC2)nc2cc3c(cc21)CCN(CC(N)CC(F)(F)F)C3=O			786039	US20250346592, Example 7	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786039	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786039&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774203	523968784							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573460	Cn1c(-c2cc3ccccc3n2CC2CC2)nc2cc3c(cc21)CCN(CC1CNCCN1)C3=O			786040	US20250346592, Example 8	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786040	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786040&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774338	523968785							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573461	CC[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccccc2n1CC1CC1)n3C			786041	US20250346592, Example 9	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786041	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786041&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774189	523968786							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573462	CC[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccccc2n1CC1CC1)n3C			786041	US20250346592, Example 9	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786041	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786041&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774189	523968786							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573463	Cn1c(-c2cc3ccccc3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)C1CC1)C3=O			786042	US20250346592, Example 10	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786042	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786042&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774302	523968787							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573464	Cn1c(-c2cc3ccccc3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)C1CC1)C3=O			786042	US20250346592, Example 10	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786042	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786042&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774302	523968787							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573465	CC(C)[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccccc2n1CC1CC1)n3C			786043	US20250346592, Example 11	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786043	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786043&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774148	523968788							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573466	CC(C)[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccccc2n1CC1CC1)n3C			786043	US20250346592, Example 11	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786043	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786043&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774148	523968788							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573467	Cn1c(-c2cc3cccnc3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786044	US20250346592, Example 12	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786044	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786044&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774222	523968789							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573468	Cn1c(-c2cc3cccnc3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786044	US20250346592, Example 12	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786044	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786044&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774222	523968789							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573469	Cn1c(-c2cc3ccccc3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H]1COCCN1)C3=O			786045	US20250346592, Example 13	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786045	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786045&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774290	523968790							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573470	Cn1c(-c2cc3ccccc3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H]1COCCN1)C3=O			786045	US20250346592, Example 13	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786045	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786045&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774290	523968790							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573471	Cn1c(C2Cc3ccccc3N2CC2CC2)nc2c1=CC1CCN(C[C@H](N)C(F)F)C(=O)C1C=2			786046	US20250346592, Example 14	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786046	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786046&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185101	523968791							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573472	Cn1c(C2Cc3ccccc3N2CC2CC2)nc2c1=CC1CCN(C[C@H](N)C(F)F)C(=O)C1C=2			786046	US20250346592, Example 14	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786046	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786046&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185101	523968791							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573473	COc1cccc2c1N(CC1CC1)[C@@H](c1nc3c(n1C)=CC1CCN(C[C@H](N)[C@@H](C)F)C(=O)C1C=3)C2			786047	6-((2S,3R)-2-amino-3-fluorobutyl)-2-(1-(cyclopropylmethyl)-7-methoxy-1H-indol-2-yl)-1-methyl-1,6,7,8-tetrahydro-5H-imidazo[4,5-g]isoquinolin-5-one::US20250346592, Example 15a	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786047	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786047&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185102	523968792							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573474	COc1cccc2c1N(CC1CC1)[C@@H](c1nc3c(n1C)=CC1CCN(C[C@H](N)[C@@H](C)F)C(=O)C1C=3)C2			786047	6-((2S,3R)-2-amino-3-fluorobutyl)-2-(1-(cyclopropylmethyl)-7-methoxy-1H-indol-2-yl)-1-methyl-1,6,7,8-tetrahydro-5H-imidazo[4,5-g]isoquinolin-5-one::US20250346592, Example 15a	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786047	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786047&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185102	523968792							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573475	COc1cccc2c1N(CC1CC1)[C@H](c1nc3c(n1C)=CC1CCN(C[C@H](N)[C@@H](C)F)C(=O)C1C=3)C2			786048	US20250346592, Example 15b	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786048	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786048&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185103	523968793							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573476	COc1cccc2c1N(CC1CC1)[C@H](c1nc3c(n1C)=CC1CCN(C[C@H](N)[C@@H](C)F)C(=O)C1C=3)C2			786048	US20250346592, Example 15b	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786048	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786048&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185103	523968793							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573477	Cc1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@@H](C)N)C5=O)n(CC3CC3)c2c1C			786049	US20250346592, Example 16	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786049	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786049&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344278	523968794							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573478	Cc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@@H](C)N)C5=O)n(CC3CC3)c12			786050	US20250346592, Example 17	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786050	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786050&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603942	523968795							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573479	COc1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@@H](C)N)C5=O)n(CC3CC3)c2c1			786051	US20250346592, Example 18	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786051	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786051&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774150	523968796							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573480	CC(C)c1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@@H](C)N)C5=O)n(CC3CC3)c12			786052	US20250346592, Example 19	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786052	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786052&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774160	523968797							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573481	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccc(C(F)(F)F)cc2n1CC1CC1)n3C			786053	US20250346592, Example 20	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786053	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786053&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604104	523968798							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573482	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccc(F)nc2n1CC1CC1)n3C			786054	US20250346592, Example 21	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786054	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786054&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774069	523968799							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573483	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccnc(Cl)c2n1CC1CC1)n3C			786055	US20250346592, Example 22	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786055	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786055&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774369	523968800							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573484	Cc1c(-c2nc3cc4c(cc3n2C)CCN(C[C@@H](C)N)C4=O)n(CC2CC2)c2ccccc12			786056	US20250346592, Example 23	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786056	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786056&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774158	523968801							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573485	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccncc2n1CC1CC1)n3C			786057	US20250346592, Example 24	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786057	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786057&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774358	523968802							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573486	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccc(Cl)cc2n1CC1CC1)n3C			786058	US20250346592, Example 25	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786058	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786058&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604127	523968803							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573487	Cc1ccc2c(c1)cc(-c1nc3cc4c(cc3n1C)CCN(C[C@@H](C)N)C4=O)n2CC1CC1			786059	US20250346592, Example 26	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786059	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786059&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774287	523968804							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573488	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2cccc(C#N)c2n1CC1CC1)n3C			786060	US20250346592, Example 27	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786060	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786060&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604016	523968805							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573489	CCc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@@H](C)N)C5=O)n(CC3CC3)c12			786061	US20250346592, Example 28	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786061	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786061&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774216	523968806							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573490	Cc1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@@H](C)N)C5=O)n(CC3CC3)c2c1			786062	US20250346592, Example 29	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786062	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786062&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774339	523968807							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573491	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2cccc(F)c2n1CC1CC1)n3C			786063	US20250346592, Example 30	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786063	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786063&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774149	523968808							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573492	COc1nccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@@H](C)N)C5=O)n(CC3CC3)c12			786064	US20250346592, Example 31	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786064	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786064&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604186	523968809							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573493	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccc(C#N)cc2n1CC1CC1)n3C			786065	US20250346592, Example 32	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786065	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786065&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603908	523968810							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573494	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2cccc(Cl)c2n1CC1CC1)n3C			786066	US20250346592, Example 33	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786066	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786066&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774350	523968811							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573495	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2cc(Cl)ccc2n1CC1CC1)n3C			786067	US20250346592, Example 34	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786067	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786067&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774231	523968812							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573496	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@@H](C)N)C5=O)n(CC3CC3)c12			786068	US20250346592, Example 35	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786068	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786068&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344170	523968813							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573497	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@@H](C)N)C5=O)n(CC3CC3)c12			786068	US20250346592, Example 35	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786068	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786068&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344170	523968813							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573498	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2cccc(C(F)(F)F)c2n1CC1CC1)n3C			786069	US20250346592, Example 36	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786069	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786069&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344122	523968814							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573499	CN[C@H](C)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2cccc(OC)c2n1CC1CC1)n3C			786070	US20250346592, Example 37	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786070	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786070&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344352	523968815							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573500	CC(C)c1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@@H](C)N)C5=O)n(CC3CC3)c2c1			786071	US20250346592, Example 38	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786071	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786071&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344223	523968816							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573501	CCc1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@@H](C)N)C5=O)n(CC3CC3)c2c1			786072	US20250346592, Example 39	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786072	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786072&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774347	523968817							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573502	COCC(C)c1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@@H](C)N)C5=O)n(CC3CC3)c2c1			786073	US20250346592, Example 40	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786073	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786073&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170407059	523968818							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573503	COCC(C)c1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@@H](C)N)C5=O)n(CC3CC3)c2c1			786074	US20250346592, Example 41	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786074	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786074&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170407059	523968819							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573504	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccc(C4COC4)cc2n1CC1CC1)n3C			786075	US20250346592, Example 42	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786075	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786075&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344433	523968820							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573505	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccc(Cl)nc2n1CC1CC1)n3C			786076	US20250346592, Example 43	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786076	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786076&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344186	523968821							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573506	COc1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@@H](C)N)C5=O)n(CC3CC3)c2n1			786077	US20250346592, Example 44	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786077	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786077&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344313	523968822							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573507	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(C1=CC2C=CC(=O)NC2N1CC1CC1)n3C			786078	US20250346592, Example 45	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786078	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786078&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185104	523968823							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573508	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1c(F)c2ccccc2n1CC1CC1)n3C			786079	US20250346592, Example 46	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786079	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786079&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344458	523968824							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573509	Cc1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c2c1			786080	US20250346592, Example 47	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786080	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786080&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774154	523968825							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573510	Cc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786081	US20250346592, Example 48	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786081	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786081&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774306	523968826							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573511	Cc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786081	US20250346592, Example 48	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786081	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786081&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774306	523968826							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573512	Cn1c(-c2cc3cccnc3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786082	US20250346592, Example 49	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786082	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786082&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774222	523968827							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573513	COc1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c2c1			786083	US20250346592, Example 50	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786083	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786083&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774352	523968828							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573514	CC(C)c1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c2c1			786084	US20250346592, Example 51	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786084	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786084&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774283	523968829							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573515	Cn1c(-c2cc3ccncc3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786085	US20250346592, Example 52	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786085	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786085&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774372	523968830							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573516	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786086	US20250346592, Example 53	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786086	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786086&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774153	523968831							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573517	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786086	US20250346592, Example 53	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786086	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786086&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774153	523968831							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573518	COc1nccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786087	US20250346592, Example 54	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786087	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786087&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604276	523968832							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573519	Cn1c(-c2cc3ccc(C(C)(C)C)cc3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786088	US20250346592, Example 55	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786088	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786088&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774359	523968833							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573520	Cn1c(-c2cc3ccc(Cl)nc3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786089	US20250346592, Example 56	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786089	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786089&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344275	523968834							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573521	Cc1cc(N2CCCS2(=O)=O)ccc1-c1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c2n1			786090	US20250346592, Example 57	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786090	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786090&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344418	523968835							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573522	Cc1cc(N2CC(C)(C)OC2=O)ccc1-c1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c2n1			786091	US20250346592, Example 58	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786091	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786091&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604169	523968836							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573523	Cn1c(-c2cc3ccc(C4CC4)nc3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786092	US20250346592, Example 59	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786092	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786092&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774188	523968837							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573524	Cc1cc(C(N)=O)c(F)cc1-c1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c2n1			786093	US20250346592, Example 60	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786093	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786093&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603987	523968838							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573525	Cc1cc(C(N)=O)c(F)cc1-c1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c2n1			786093	US20250346592, Example 60	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786093	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786093&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603987	523968838							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573526	CCc1nc(N2CCOC2=O)ccc1-c1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c2n1			786094	US20250346592, Example 61	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786094	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786094&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344262	523968839							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573527	COc1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c2n1			786095	US20250346592, Example 62	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786095	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786095&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344084	523968840							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573528	CNC(=O)c1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c2n1			786096	US20250346592, Example 63	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786096	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786096&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344368	523968841							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573529	CN(C)C(=O)c1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c2n1			786097	US20250346592, Example 64	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786097	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786097&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344133	523968842							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573530	COc1cc(F)cc2c1N(CC1CC1)C(c1nc3c(n1C)=CC1CCN(C[C@H](N)CF)C(=O)C1C=3)C2			786098	US20250346592, Example 65	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786098	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786098&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185105	523968843							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573531	COc1cc(F)cc2c1N(CC1CC1)C(c1nc3c(n1C)=CC1CCN(C[C@H](N)CF)C(=O)C1C=3)C2			786098	US20250346592, Example 65	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786098	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786098&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185105	523968843							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573532	COc1c(F)ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786099	US20250346592, Example 66	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786099	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786099&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344131	523968844							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573533	Cn1c(C2Cc3ccc(C(=O)O)cc3N2CC2CC2)nc2c1=CC1CCN(C[C@H](N)CF)C(=O)C1C=2			786100	US20250346592, Example 67	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786100	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786100&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185106	523968845							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573534	COC1CCN(c2ccc3c(c2)N(CC2CC2)C(c2nc4c(n2C)=CC2CCN(C[C@H](N)CF)C(=O)C2C=4)C3)CC1			786101	US20250346592, Example 68	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786101	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786101&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185107	523968846							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573535	COC1CCN(c2ccc3c(c2)N(CC2CC2)C(c2nc4c(n2C)=CC2CCN(C[C@H](N)CF)C(=O)C2C=4)C3)CC1			786101	US20250346592, Example 68	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786101	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786101&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185107	523968846							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573536	CN(C)c1cccc2c1N(CC1CC1)C(c1nc3c(n1C)=CC1CCN(C[C@H](N)CF)C(=O)C1C=3)C2			786102	US20250346592, Example 69	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786102	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786102&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185108	523968847							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573537	Cn1c(-c2cc3cccc(N4CCOCC4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786103	US20250346592, Example 70	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786103	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786103&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604268	523968848							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573538	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccccc2n1CC1CCC1)n3C			786104	US20250346592, Example 71	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786104	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786104&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774212	523968849							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573539	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccccc2n1CC1CCCC1)n3C			786105	US20250346592, Example 72	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786105	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786105&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774070	523968850							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573540	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccccc2n1CC12CC(C1)C2)n3C			786106	US20250346592, Example 73	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786106	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786106&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774265	523968851							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573541	CC(C)Cn1c(-c2nc3cc4c(cc3n2C)CCN(C[C@@H](C)N)C4=O)cc2ccccc21			786107	US20250346592, Example 74	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786107	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786107&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604070	523968852							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573542	COC1CC(Cn2c(-c3nc4cc5c(cc4n3C)CCN(C[C@@H](C)N)C5=O)cc3ccccc32)C1			786108	US20250346592, Example 75	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786108	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786108&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774353	523968853							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573543	COCCn1c(-c2nc3cc4c(cc3n2C)CCN(C[C@@H](C)N)C4=O)cc2ccccc21			786109	US20250346592, Example 76	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786109	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786109&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774263	523968854							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573544	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccccc2n1CCC1CC1)n3C			786110	US20250346592, Example 77	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786110	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786110&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774355	523968855							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573545	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccccc2n1Cc1ccccc1)n3C			786111	US20250346592, Example 78	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786111	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786111&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604003	523968856							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573546	CCn1c(-c2nc3cc4c(cc3n2C)CCN(C[C@@H](C)N)C4=O)cc2ccccc21			786112	US20250346592, Example 79	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786112	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786112&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604198	523968857							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573547	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccccc2n1Cc1cccnc1)n3C			786113	US20250346592, Example 80	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786113	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786113&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774230	523968858							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573548	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccccc2n1Cc1ccncc1)n3C			786114	US20250346592, Example 81	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786114	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786114&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603892	523968859							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573549	C=CCn1c(-c2nc3cc4c(cc3n2C)CCN(C[C@@H](C)N)C4=O)cc2ccccc21			786115	US20250346592, Example 82	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786115	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786115&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604050	523968860							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573550	Cc1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@@H](C)N)C5=O)n(CC3CCC3)c2c1			786116	US20250346592, Example 83	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786116	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786116&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185109	523968861							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573551	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccccc2n1Cc1ccccn1)n3C			786117	US20250346592, Example 84	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786117	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786117&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774129	523968862							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573552	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccccc2n1CC1CC1)n3C			786118	US20250346592, Example 85	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786118	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786118&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344334	523968863							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573553	COCCn1c(-c2nc3cc4c(cc3n2C)CCN(C[C@@H](C)N)C4=O)cc2cccc(C)c21			786119	US20250346592, Example 87	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786119	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786119&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603932	523968864							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573554	COCCn1c(-c2nc3cc4c(cc3n2C)CCN(C[C@@H](C)N)C4=O)cc2cccc(OC)c21			786120	US20250346592, Example 88	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786120	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786120&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774293	523968865							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573555	Cc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@@H](C)N)C5=O)n(CC3CCC3)c12			786121	US20250346592, Example 89	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786121	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786121&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774211	523968866							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573556	CCn1c(-c2nc3cc4c(cc3n2C)CCN(C[C@@H](C)N)C4=O)cc2cccc(OC)c21			786122	US20250346592, Example 90	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786122	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786122&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774124	523968867							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573557	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@@H](C)N)C5=O)n(CCOC3CC3)c12			786123	US20250346592, Example 91	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786123	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786123&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603904	523968868							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573558	C[C@@H](N)CN1CCc2cc3c(cc2C1=O)nc(-c1cc2ccccc2n1CC(C)(C)O)n3C			786124	US20250346592, Example 92	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786124	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786124&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344296	523968869							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573559	Cn1c(-c2cc3ccccc3n2Cc2ccno2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786125	US20250346592, Example 93	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786125	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786125&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344062	523968870							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573560	COCCn1c(-c2nc3cc4c(cc3n2C)CCN(C[C@H](N)CF)C4=O)cc2ccccc21			786126	US20250346592, Example 94	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786126	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786126&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603941	523968871							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573561	Cn1cc(Cn2c(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)cc3ccccc32)cn1			786127	US20250346592, Example 95	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786127	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786127&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774121	523968872							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573562	Cn1nccc1Cn1c(-c2nc3cc4c(cc3n2C)CCN(C[C@H](N)CF)C4=O)cc2ccccc21			786128	US20250346592, Example 96	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786128	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786128&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774209	523968873							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573563	Cc1cc(Cn2c(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)cc3ccccc32)on1			786129	US20250346592, Example 97	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786129	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786129&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774135	523968874							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573564	Cn1c(-c2cc3ccccc3n2Cc2ccon2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786130	US20250346592, Example 98	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786130	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786130&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774186	523968875							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573565	Cc1nnc(Cn2c(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)cc3ccccc32)o1			786131	US20250346592, Example 99	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786131	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786131&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774131	523968876							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573566	Cc1cc(Cn2c(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)cc3ccccc32)no1			786132	US20250346592, Example 100	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786132	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786132&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774057	523968877							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573567	Cn1c(-c2cc3ccccc3n2CC2CCC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786133	US20250346592, Example 101	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786133	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786133&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774285	523968878							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573568	COCCN1c2c(cccc2OC)CC1c1nc2c(n1C)=CC1CCN(C[C@H](N)CF)C(=O)C1C=2			786134	US20250346592, Example 102	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786134	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786134&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185110	523968879							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573569	COCCN1c2c(cccc2OC)CC1c1nc2c(n1C)=CC1CCN(C[C@H](N)CF)C(=O)C1C=2			786134	US20250346592, Example 102	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786134	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786134&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185110	523968879							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573570	COCCn1c(-c2nc3cc4c(cc3n2C)CCN(C[C@H](N)CF)C4=O)cc2ccc(OC)cc21			786135	US20250346592, Example 103	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786135	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786135&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604173	523968880							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573571	COCCn1c(-c2nc3cc4c(cc3n2C)CCN(C[C@H](N)CF)C4=O)cc2ccc(Cl)nc21			786136	US20250346592, Example 104	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786136	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786136&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774291	523968881							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573572	COCCn1c(-c2nc3cc4c(cc3n2C)CCN(C[C@H](N)CF)C4=O)cc2ccc(OC)nc21			786137	US20250346592, Example 105	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786137	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786137&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604048	523968882							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573573	COCCn1c(-c2nc3cc4c(cc3n2C)CCN(C[C@H](N)CF)C4=O)cc2cccnc21			786138	US20250346592, Example 106	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786138	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786138&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774337	523968883							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573574	CCn1c(-c2nc3cc4c(cc3n2C)CCN(C[C@H](N)CF)C4=O)cc2cccc(OC)c21			786139	US20250346592, Example 107	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786139	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786139&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603925	523968884							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573575	CCn1c(-c2nc3cc4c(cc3n2C)CCN(C[C@H](N)CF)C4=O)cc2ccc(OC)nc21			786140	US20250346592, Example 108	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786140	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786140&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604160	523968885							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573576	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(C(C)C)c12			786141	US20250346592, Example 109	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786141	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786141&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185111	523968886							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573577	COCCn1c(-c2nc3cc4c(cc3n2C)CCN(C[C@H](N)CF)C4=O)cc2ccnc(OC)c21			786142	US20250346592, Example 110	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786142	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786142&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604017	523968887							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573578	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3ccno3)c12			786143	US20250346592, Example 111	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786143	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786143&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603896	523968888							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573579	COc1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3ccno3)c2c1			786144	US20250346592, Example 112	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786144	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786144&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774304	523968889							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573580	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3cc(C)no3)c12			786145	US20250346592, Example 113	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786145	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786145&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774205	523968890							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573581	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3cc(C)no3)c12			786145	US20250346592, Example 113	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786145	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786145&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774205	523968890							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573582	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3cn(C)cn3)c12			786146	US20250346592, Example 114	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786146	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786146&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774300	523968891							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573583	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3cc[nH]n3)c12			786147	US20250346592, Example 115	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786147	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786147&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774161	523968892							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573584	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3nnco3)c12			786148	US20250346592, Example 116	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786148	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786148&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774151	523968893							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573585	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3cnco3)c12			786149	US20250346592, Example 117	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786149	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786149&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774220	523968894							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573586	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3ccns3)c12			786150	US20250346592, Example 118	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786150	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786150&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774195	523968895							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573587	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3ncco3)c12			786151	US20250346592, Example 119	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786151	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786151&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774120	523968896							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573588	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3ncco3)c12			786151	US20250346592, Example 119	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786151	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786151&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774120	523968896							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573589	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3ncno3)c12			786152	US20250346592, Example 120	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786152	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786152&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774227	523968897							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573590	Cn1c(-c2cc3cccnc3n2Cc2ccno2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786153	US20250346592, Example 121	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786153	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786153&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774368	523968898							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573591	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC(=O)N(C)C)c12			786154	US20250346592, Example 122	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786154	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786154&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774370	523968899							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573592	COC[C@H](C)n1c(-c2nc3cc4c(cc3n2C)CCN(C[C@H](N)CF)C4=O)cc2cccc(OC)c21			786155	US20250346592, Example 123a	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786155	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786155&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185112	523968900							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573593	COC[C@@H](C)n1c(-c2nc3cc4c(cc3n2C)CCN(C[C@H](N)CF)C4=O)cc2cccc(OC)c21			786156	US20250346592, Example 123b	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786156	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786156&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185113	523968901							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573594	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3nc(C)co3)c12			786157	US20250346592, Example 124	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786157	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786157&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774197	523968902							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573595	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3nc(C)co3)c12			786157	US20250346592, Example 124	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786157	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786157&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774197	523968902							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573596	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3ncc(C)o3)c12			786158	US20250346592, Example 125	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786158	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786158&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774299	523968903							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573597	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3cccnn3)c12			786159	US20250346592, Example 126	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786159	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786159&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774336	523968904							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573598	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3nccs3)c12			786160	US20250346592, Example 127	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786160	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786160&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774207	523968905							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573599	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3nccs3)c12			786160	US20250346592, Example 127	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786160	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786160&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774207	523968905							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573600	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3cnccn3)c12			786161	US20250346592, Example 128	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786161	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786161&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774164	523968906							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573601	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3nc(C)no3)c12			786162	US20250346592, Example 129	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786162	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786162&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774163	523968907							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573602	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(C[C@@H](C)OC)c12			786163	US20250346592, Example 130	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786163	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786163&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185114	523968908							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573603	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(C[C@H](C)OC)c12			786164	US20250346592, Example 131	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786164	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786164&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185115	523968909							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573604	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(C[C@H]3CCCO3)c12			786165	US20250346592, Example 132	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786165	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786165&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774235	523968910							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573605	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(C[C@@H]3CCCO3)c12			786166	US20250346592, Example 133	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786166	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786166&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774159	523968911							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573606	CCn1c(-c2nc3cc4c(cc3n2C)CCN(C[C@H](N)CF)C4=O)cc2ccccc21			786167	US20250346592, Example 134	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786167	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786167&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604199	523968912							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573607	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CCOC(F)F)c12			786168	US20250346592, Example 135	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786168	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786168&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603935	523968913							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573608	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3cc(Cl)no3)c12			786169	US20250346592, Example 136	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786169	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786169&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774152	523968914							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573609	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3cc(C#N)no3)c12			786170	US20250346592, Example 137	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786170	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786170&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604249	523968915							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573610	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3ccoc3)c12			786171	US20250346592, Example 138	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786171	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786171&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603958	523968916							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573611	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3oncc3C)c12			786172	US20250346592, Example 139	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786172	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786172&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774219	523968917							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573612	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3ccc(C#N)o3)c12			786173	US20250346592, Example 140	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786173	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786173&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604011	523968918							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573613	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3ccco3)c12			786174	US20250346592, Example 141	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786174	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786174&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774229	523968919							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573614	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3ocnc3C)c12			786175	US20250346592, Example 142	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786175	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786175&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774192	523968920							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573615	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3ccc(C)o3)c12			786176	US20250346592, Example 143	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786176	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786176&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604207	523968921							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573616	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3ccnnc3)c12			786177	US20250346592, Example 144	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786177	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786177&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774136	523968922							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573617	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3coc(C)n3)c12			786178	US20250346592, Example 145	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786178	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786178&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604182	523968923							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573618	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3cc(N)no3)c12			786179	US20250346592, Example 146	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786179	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786179&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774053	523968924							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573619	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(Cc3cc(N)no3)c12			786179	US20250346592, Example 146	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786179	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786179&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774053	523968924							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573620	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3(OC)CC3)c12			786180	US20250346592, Example 147	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786180	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786180&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185116	523968925							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573621	Cn1c(-c2cc3cccc(C#N)c3n2Cc2ccno2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786181	US20250346592, Example 148	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786181	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786181&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344086	523968926							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573622	Cn1c(-c2cc3cccc(OCC4COC4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786182	US20250346592, Example 149	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786182	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786182&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344111	523968927							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573623	Cn1c(-c2cc3cccc(OCCn4cncn4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786183	US20250346592, Example 150	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786183	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786183&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774295	523968928							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573624	Cn1c(-c2cc3cccc(OCCn4cncn4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786183	US20250346592, Example 150	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786183	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786183&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774295	523968928							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573625	Cn1c(-c2cc3cccc(OCC4CNC(=O)C4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786184	US20250346592, Example 151	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786184	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786184&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604280	523968929							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573626	Cn1c(-c2cc3cccc(OCC4CNC4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786185	US20250346592, Example 152	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786185	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786185&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603950	523968930							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573627	COCCOc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786186	US20250346592, Example 153	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786186	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786186&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604122	523968931							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573628	CN(C)CCOc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786187	US20250346592, Example 154	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786187	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786187&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603979	523968932							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573629	Cn1c(-c2cc3cccc(OCCn4cccn4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786188	US20250346592, Example 155	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786188	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786188&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604061	523968933							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573630	Cn1c(-c2cc3cccc(OC[C@@H]4CCC(=O)N4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786189	US20250346592, Example 156	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786189	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786189&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774269	523968934							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573631	Cn1c(-c2cc3cccc(OC[C@H]4CCC(=O)N4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786190	US20250346592, Example 157	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786190	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786190&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774303	523968935							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573632	Cn1c(-c2cc3cccc(OCCN4CCOCC4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786191	US20250346592, Example 158	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786191	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786191&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603995	523968936							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573633	Cn1c(-c2cc3cccc(OC[C@@H]4CNCCO4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786192	US20250346592, Example 159	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786192	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786192&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774348	523968937							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573634	Cn1c(-c2cc3cccc(OC[C@H]4CNCCO4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786193	US20250346592, Example 160	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786193	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786193&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774360	523968938							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573635	Cn1c(-c2cc3cccc(OCC4CCOCC4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786194	US20250346592, Example 161	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786194	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786194&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604007	523968939							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573636	Cc1nc(C)n(CCOc2cccc3cc(-c4nc5cc6c(cc5n4C)CCN(C[C@H](N)CF)C6=O)n(CC4CC4)c23)n1			786195	US20250346592, Example 162	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786195	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786195&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603905	523968940							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573637	Cc1ncnn1CCOc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786196	US20250346592, Example 163	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786196	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786196&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603952	523968941							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573638	Cc1ncn(CCOc2cccc3cc(-c4nc5cc6c(cc5n4C)CCN(C[C@H](N)CF)C6=O)n(CC4CC4)c23)n1			786197	US20250346592, Example 164	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786197	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786197&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604191	523968942							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573639	Cc1nccn1CCOc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786198	US20250346592, Example 165	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786198	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786198&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603884	523968943							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573640	Cc1nccn1CCOc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786198	US20250346592, Example 165	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786198	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786198&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603884	523968943							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573641	Cn1c(-c2cc3cccc(OCc4cnco4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786199	US20250346592, Example 166	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786199	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786199&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603982	523968944							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573642	Cn1c(-c2cc3cccc(OCc4ccon4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786200	US20250346592, Example 167	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786200	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786200&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604014	523968945							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573643	Cn1c(-c2cc3cccc(OC[C@H]4CNC(=O)O4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786201	US20250346592, Example 168	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786201	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786201&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604112	523968946							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573644	Cn1cncc1CCOc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786202	US20250346592, Example 169	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786202	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786202&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170407294	523968947							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573645	Cn1cncc1CCOc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786202	US20250346592, Example 169	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786202	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786202&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170407294	523968947							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573646	Cn1c(-c2cc3cccc(OCCc4ccon4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786203	US20250346592, Example 170	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786203	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786203&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604073	523968948							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573647	Cn1c(-c2cc3cccc(OCc4ccnnc4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786204	US20250346592, Example 171	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786204	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786204&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604142	523968949							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573648	Cn1c(-c2cc3cccc(OCC4COC(=O)N4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786205	US20250346592, Example 172	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786205	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786205&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604049	523968950							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573649	Cn1c(-c2cc3cccc(OCCc4cc[nH]n4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786206	US20250346592, Example 173	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786206	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786206&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604279	523968951							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573650	Cn1c(-c2cc3cccc(OCc4ccn[nH]4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786207	US20250346592, Example 174	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786207	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786207&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774146	523968952							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573651	Cn1c(-c2cc3cccc(OCc4ccn[nH]4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786207	US20250346592, Example 174	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786207	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786207&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774146	523968952							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573652	Cn1c(-c2cc3cccc(OCc4ccno4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786208	US20250346592, Example 175	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786208	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786208&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603957	523968953							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573653	Cn1c(-c2cc3cccc(OCc4nnco4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786209	US20250346592, Example 176	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786209	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786209&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604255	523968954							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573654	Cc1nnc(COc2cccc3cc(-c4nc5cc6c(cc5n4C)CCN(C[C@H](N)CF)C6=O)n(CC4CC4)c23)o1			786210	US20250346592, Example 177	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786210	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786210&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604228	523968955							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573655	Cn1c(-c2cc3cccc(OCCC4CNC(=O)C4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786211	US20250346592, Example 178	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786211	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786211&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774292	523968956							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573656	Cn1c(-c2cc3cccc(OCCC4CNC(=O)C4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786212	US20250346592, Example 179	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786212	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786212&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774292	523968957							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573657	Cn1c(-c2cc3cccc(OCCn4cccc4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786213	US20250346592, Example 180	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786213	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786213&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604069	523968958							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573658	Cn1c(-c2cc3cccc(OCCn4ccnn4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786214	US20250346592, Example 181	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786214	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786214&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604134	523968959							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573659	Cn1c(-c2cc3cccc(OCCn4ccnn4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786214	US20250346592, Example 181	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786214	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786214&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604134	523968959							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573660	Cc1nncn1CCOc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786215	US20250346592, Example 182	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786215	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786215&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603955	523968960							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573661	Cn1c(-c2cc3cccc(OCc4cccnn4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786216	US20250346592, Example 183	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786216	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786216&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604189	523968961							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573662	CN1CC(COc2cccc3cc(-c4nc5cc6c(cc5n4C)CCN(C[C@H](N)CF)C6=O)n(CC4CC4)c23)CC1=O			786217	US20250346592, Example 184	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786217	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786217&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774286	523968962							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573663	CN1CC(COc2cccc3cc(-c4nc5cc6c(cc5n4C)CCN(C[C@H](N)CF)C6=O)n(CC4CC4)c23)CC1=O			786217	US20250346592, Example 184	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786217	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786217&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774286	523968962							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573664	Cn1c(-c2cc3cccc(OCC4CC(F)(F)C(=O)N4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786218	US20250346592, Example 185	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786218	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786218&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774145	523968963							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573665	Cn1c(-c2cc3cccc(OCCn4cnnn4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786219	US20250346592, Example 186	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786219	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786219&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604105	523968964							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573666	Cn1c(-c2cc3cccc(OCCn4cnnn4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786219	US20250346592, Example 186	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786219	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786219&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604105	523968964							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573667	Cn1c(-c2cc3cccc(OC[C@@H]4COCCN4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786220	US20250346592, Example 187	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786220	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786220&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344182	523968965							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573668	Cn1c(-c2cc3cccc(OC[C@@H]4COCCN4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786221	US20250346592, Example 188	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786221	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786221&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344182	523968966							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573669	Cn1c(-c2cc3cccc(OCc4cocn4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786222	US20250346592, Example 189	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786222	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786222&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604213	523968967							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573670	Cn1c(-c2cc3cccc(OC[C@@H]4CNC(=O)C4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786223	US20250346592, Example 190	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786223	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786223&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604082	523968968							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573671	Cn1c(-c2cc3cccc(OC[C@@H]4CNC(=O)C4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786223	US20250346592, Example 190	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786223	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786223&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604082	523968968							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573672	CC(CCO)Oc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786224	US20250346592, Example 191	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786224	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786224&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185117	523968969							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573673	C[C@H](CCO)Oc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786225	US20250346592, Example 192	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786225	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786225&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603968	523968970							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573674	Cn1c(-c2cc3cccc(OCc4cn[nH]c4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786226	US20250346592, Example 193	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786226	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786226&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604096	523968971							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573675	Cn1c(-c2cc3cccc(OCCc4cnco4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786227	US20250346592, Example 194	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786227	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786227&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344274	523968972							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573676	Cn1c(-c2cc3cccc(OCCc4ccno4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786228	US20250346592, Example 195	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786228	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786228&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604231	523968973							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573677	Cn1c(-c2cc3cccc(OCCc4ccno4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786228	US20250346592, Example 195	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786228	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786228&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604231	523968973							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573678	Cn1c(-c2cc3cccc(OCCc4cocn4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786229	US20250346592, Example 196	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786229	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786229&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604174	523968974							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573679	CC(Oc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12)c1ccno1			786230	US20250346592, Example 197	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786230	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786230&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604250	523968975							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573680	Cn1c(-c2cc3cccc(OCCN4C=NCC4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786231	US20250346592, Example 198	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786231	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786231&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185118	523968976							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573681	Cn1c(-c2cc3cccc(OCCN4C=NCC4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786231	US20250346592, Example 198	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786231	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786231&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			178185118	523968976							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573682	Cn1c(-c2cc3cccc(OCCc4c[nH]nn4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786232	US20250346592, Example 199	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786232	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786232&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604226	523968977							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573683	Cn1c(-c2cc3cccc(OCCc4c[nH]nn4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786232	US20250346592, Example 199	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786232	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786232&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604226	523968977							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573684	COC(=O)NC[C@@H](C)Oc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786233	US20250346592, Example 200	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786233	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786233&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604188	523968978							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573685	COC(=O)N(C)CCOc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786234	US20250346592, Example 201	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786234	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786234&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604036	523968979							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573686	COC(=O)N(C)CCOc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786234	US20250346592, Example 201	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786234	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786234&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604036	523968979							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573687	COC(=O)NC[C@H](C)Oc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786235	US20250346592, Example 202	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786235	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786235&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604238	523968980							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573688	Cn1c(-c2cc3cccc(OCCc4cc[nH]c4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786236	US20250346592, Example 203	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786236	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786236&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604254	523968981							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573689	Cn1c(-c2cc3cccc(OCCc4cnoc4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786237	US20250346592, Example 204	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786237	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786237&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604246	523968982							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573690	Cn1c(-c2cc3cccc(OCCc4cnoc4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786237	US20250346592, Example 204	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786237	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786237&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604246	523968982							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573691	Cn1c(-c2cc3cccc(OCCO)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786238	US20250346592, Example 205	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786238	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786238&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344375	523968983							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573692	Cn1c(-c2cc3cccc(OCCO)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786238	US20250346592, Example 205	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786238	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786238&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344375	523968983							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573693	Cn1c(-c2cc3cccc(OC[C@@H]4CNC(=O)O4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786239	US20250346592, Example 206	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786239	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786239&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604181	523968984							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573694	Cn1c(-c2cc3cccc(OC[C@@H]4CNC(=O)O4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786239	US20250346592, Example 206	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786239	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786239&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604181	523968984							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573695	COC(=O)NCCOc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786240	US20250346592, Example 207	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786240	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786240&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603970	523968985							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573696	COC(=O)NCCOc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786240	US20250346592, Example 207	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786240	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786240&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603970	523968985							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573697	COC(=O)N[C@@H](C)COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786241	US20250346592, Example 208	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786241	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786241&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604095	523968986							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573698	COC(=O)N[C@@H](C)COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786241	US20250346592, Example 208	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786241	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786241&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604095	523968986							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573699	COC(=O)N[C@H](C)COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786242	US20250346592, Example 209	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786242	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786242&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603936	523968987							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573700	Cn1c(-c2cc3cccc(OCCn4cnnc4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786243	US20250346592, Example 210	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786243	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786243&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604258	523968988							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573701	Cn1c(-c2cc3cccc(OCCn4cnnc4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786243	US20250346592, Example 210	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786243	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786243&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604258	523968988							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573702	CNC(=O)OCCOc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786244	US20250346592, Example 211	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786244	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786244&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344303	523968989							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573703	C[C@@H](COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12)n1ccnc1			786245	US20250346592, Example 212	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786245	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786245&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344417	523968990							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573704	C[C@@H](COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12)n1ccnc1			786245	US20250346592, Example 212	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786245	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786245&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344417	523968990							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573705	C[C@H](COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12)n1ccnc1			786246	US20250346592, Example 213	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786246	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786246&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603976	523968991							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573706	C[C@H](COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12)n1ccnc1			786246	US20250346592, Example 213	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786246	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786246&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603976	523968991							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573707	Cn1c(-c2cc3cccc(OCC(C)(C)O)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786247	US20250346592, Example 214	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786247	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786247&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774349	523968992							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573708	Cn1c(-c2cc3cccc(OC[C@@H](O)C(F)(F)F)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786248	US20250346592, Example 215	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786248	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786248&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603954	523968993							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573709	Cn1c(-c2cc3cccc(OC[C@H](O)C(F)(F)F)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786249	US20250346592, Example 216	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786249	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786249&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604067	523968994							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573710	C[C@H](COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12)n1cnc(F)c1			786250	US20250346592, Example 217	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786250	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786250&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344284	523968995							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573711	Cn1c(-c2cc3cccc(OCCO)c3n2Cc2ccno2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786251	US20250346592, Example 218	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786251	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786251&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344409	523968996							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573712	Cn1c(-c2cc3cccc(OCC4CCNC4=O)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786252	US20250346592, Example 219	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786252	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786252&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344260	523968997							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573713	Cn1c(-c2cc3cccc(OCC4(C)CNC(=O)C4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786253	US20250346592, Example 220	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786253	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786253&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603945	523968998							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573714	Cn1c(-c2cc3cccc(OCC4(C)CNC(=O)C4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786254	US20250346592, Example 221	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786254	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786254&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603945	523968999							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573715	C[C@@H](Cn1ccnc1)Oc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786255	US20250346592, Example 222	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786255	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786255&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344321	523969000							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573716	C[C@@H](Cn1ccnc1)Oc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786255	US20250346592, Example 222	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786255	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786255&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344321	523969000							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573717	C[C@H](Cn1ccnc1)Oc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786256	US20250346592, Example 223	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786256	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786256&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603997	523969001							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573718	C[C@H](Cn1ccnc1)Oc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786256	US20250346592, Example 223	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786256	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786256&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603997	523969001							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573719	Cn1c(-c2cc3cccc(OCCn4cnc(C#N)n4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786257	(S)-1-(2-((2-(6-(2-amino-3-fluoropropyl)-1-methyl-5-oxo-5,6,7,8-tetrahydro-1H-imidazo[4,5-g]isoquinolin-2-yl)-1-(cyclopropylmethyl)-1H-indol-7-yl)oxy)ethyl)-1H-1,2,4-triazole-5-carbonitrile::US20250346592, Example 224	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786257	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786257&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344399	523969002							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573720	Cn1c(-c2cc3cccc(OCCn4ncnc4C#N)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786258	US20250346592, Example 225	Protein-arginine deiminase type-4	Homo sapiens		>1000							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786258	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786258&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344090	523969003							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573721	Cn1c(-c2cc3cccc(O[C@@H](F)Cn4ccnc4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786259	6-((S)-2-amino-3-fluoropropyl)-2-(1-(cyclopropylmethyl)-7-((R)-1-fluoro-2-(1H-imidazol-1-yl)ethoxy)-1H-indol-2-yl)-1-methyl-1,6,7,8-tetrahydro-5H-imidazo[4,5-g]isoquinolin-5-one::US20250346592, Example 226a	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786259	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786259&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344351	523969004							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573722	Cn1c(-c2cc3cccc(O[C@H](F)Cn4ccnc4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786260	US20250346592, Example 226b	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786260	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786260&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344164	523969005							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573723	Cn1c(-c2cc3cccc(/C=C/Cn4ccnc4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786261	US20250346592, Example 227	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786261	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786261&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344103	523969006							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573724	Cn1c(-c2cc3cccc(/C=C/Cn4ccnc4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786261	US20250346592, Example 227	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786261	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786261&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344103	523969006							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573725	Cn1c(-c2cc3cccc(CCCn4ccnc4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786262	US20250346592, Example 228	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786262	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786262&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344290	523969007							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573726	Cn1c(-c2cc3cccc(CCCn4ccnc4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786262	US20250346592, Example 228	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786262	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786262&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344290	523969007							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573727	Cn1c(-c2cc3cccc(OCC4CNC(=O)C4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786263	US20250346592, Example 229	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786263	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786263&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604280	523969008							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573728	Cn1c(-c2cc3cccc(OCC4CNC(=O)C4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H](N)CF)C3=O			786263	US20250346592, Example 229	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786263	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786263&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604280	523969008							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573729	C[C@H](COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@@H](C)N)C5=O)n(CC3CC3)c12)n1cnc(F)c1			786264	US20250346592, Example 230	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786264	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786264&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344413	523969009							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573730	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H]3COCCN3)C5=O)n(CC3CC3)c12			786265	US20250346592, Example 231	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786265	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786265&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344213	523969010							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573731	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H]3COCCN3)C5=O)n(CC3CC3)c12			786265	US20250346592, Example 231	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786265	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786265&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344213	523969010							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573732	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H]3COCCN3)C5=O)n(Cc3ncco3)c12			786266	US20250346592, Example 232	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786266	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786266&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774284	523969011							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573733	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H]3COCCN3)C5=O)n(Cc3ncco3)c12			786266	US20250346592, Example 232	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786266	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786266&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774284	523969011							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573734	COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H]3COCCN3)C5=O)n(CCOC(F)F)c12			786267	US20250346592, Example 233	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786267	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786267&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170603894	523969012							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573735	Cn1c(-c2cc3cccc(OCCn4cnnc4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H]1COCCN1)C3=O			786268	US20250346592, Example 234	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786268	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786268&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344388	523969013							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573736	Cn1c(-c2cc3cccc(OCCn4cnnc4)c3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H]1COCCN1)C3=O			786268	US20250346592, Example 234	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786268	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786268&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344388	523969013							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573737	C[C@H](COc1cccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H]3COCCN3)C5=O)n(CC3CC3)c12)n1cnc(F)c1			786269	US20250346592, Example 235	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786269	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786269&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344189	523969014							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573738	Cn1c(-c2cc3ccccc3n2CC2CC2)nc2cc3c(c(F)c21)CCN(C[C@H](N)CF)C3=O			786270	US20250346592, Example 236	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786270	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786270&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344258	523969015							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573739	Cn1c(-c2cc3ccccc3n2CC2CC2)nc2cc3c(c(F)c21)CCN(C[C@H](N)CF)C3=O			786270	US20250346592, Example 236	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786270	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786270&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344258	523969015							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573740	C[C@@H](N)CN1CCc2c(cc3nc(-c4cc5ccccc5n4CC4CC4)n(C)c3c2F)C1=O			786271	US20250346592, Example 237	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786271	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786271&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774333	523969016							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573741	C[C@@H](N)CN1CCc2c(cc3nc(-c4cc5ccccc5n4CC4CC4)n(C)c3c2F)C1=O			786271	US20250346592, Example 237	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786271	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786271&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774333	523969016							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573742	COc1cccc2cc(-c3nc4cc5c(c(F)c4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786272	US20250346592, Example 238	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786272	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786272&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774213	523969017							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573743	COc1cccc2cc(-c3nc4cc5c(c(F)c4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12			786272	US20250346592, Example 238	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786272	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786272&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774213	523969017							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573744	COc1ccc2cc(-c3nc4cc5c(c(F)c4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c2c1			786273	US20250346592, Example 239	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786273	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786273&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604217	523969018							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573745	COc1cccc2cc(-c3nc4cc5c(c(F)c4n3C)CCN(C[C@H]3COCCN3)C5=O)n(CC3CC3)c12			786274	US20250346592, Example 240	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786274	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786274&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604148	523969019							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573746	C[C@H](COc1cccc2cc(-c3nc4cc5c(c(F)c4n3C)CCN(C[C@H](N)CF)C5=O)n(CC3CC3)c12)n1cnc(F)c1			786275	US20250346592, Example 241	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786275	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786275&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774234	523969020							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573747	C[C@H](COc1cccc2cc(-c3nc4cc5c(c(F)c4n3C)CCN(C[C@H]3COCCN3)C5=O)n(CC3CC3)c12)n1cnc(F)c1			786276	US20250346592, Example 242	Protein-arginine deiminase type-4	Homo sapiens		<10							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786276	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786276&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774356	523969021							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573748	CC(=O)N1CCC(c2cccc3cc(-c4nc5cc6c(cc5n4C)CCN(C[C@H]4COCCN4)C6=O)n(CC4CC4)c23)CC1			786277	US20250346592, Example 243	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786277	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786277&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344149	523969022							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573749	COCC(=O)N1CCC(c2cccc3cc(-c4nc5cc6c(cc5n4C)CCN(C[C@H]4COCCN4)C6=O)n(CC4CC4)c23)CC1			786278	US20250346592, Example 244	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786278	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786278&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170604076	523969023							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573750	Cc1cc(C(N)=O)c(F)cc1-c1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H]3COCCN3)C5=O)n(CC3CC3)c2n1			786279	US20250346592, Example 245	Protein-arginine deiminase type-4	Homo sapiens		 300							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786279	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786279&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344323	523969024							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573751	Cc1cc(N2CCCS2(=O)=O)ccc1-c1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H]3COCCN3)C5=O)n(CC3CC3)c2n1			786280	US20250346592, Example 246	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786280	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786280&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774272	523969025							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573752	Cc1cc(N2CC(C)(C)OC2=O)ccc1-c1ccc2cc(-c3nc4cc5c(cc4n3C)CCN(C[C@H]3COCCN3)C5=O)n(CC3CC3)c2n1			786281	US20250346592, Example 247	Protein-arginine deiminase type-4	Homo sapiens		 55							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786281	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786281&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			177774226	523969026							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573753	Cn1c(-c2cc3ccc(-c4cccc(O)c4F)nc3n2CC2CC2)nc2cc3c(cc21)CCN(C[C@H]1COCCN1)C3=O			786282	US20250346592, Example 248	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786282	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786282&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344387	523969027							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																		
1573754	COC1CCN(c2ccc3cc(-c4nc5cc6c(cc5n4C)CCN(C[C@H]4COCCN4)C6=O)n(CC4CC4)c3c2)CC1			786283	US20250346592, Example 249	Protein-arginine deiminase type-4	Homo sapiens		 750							US Patent		10.7270/Q2NS10PS			US20250346592	Antropow, AH; Seletsky, BM; Ross, AG; Zhu, X; Gormisky, PE; Miao, G; Niu, D; Zhu, Z; Cuervo, JH	11/13/2025	3/4/2026	Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=786283	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4839&target=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=786283&enzyme=Protein-arginine+deiminase+type-4&column=ki&startPg=0&Increment=50&submit=Search			170344220	523969028							1	MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP	3APM,9HUJ,9HUI,9HUH,8GOD	Protein-arginine deiminase type-4	PADI4_HUMAN	Q9UM07	A8K392 B2RBW0 Q5VTZ8 Q70SX4